Healthé Trim Fat Burner Review & Information

If you're old enough, you might remember the movie "Valley Girl," which glorified 1980's teen "air-headedness". While I never I saw it myself, I remember a few girls in high school who adopted the vernacular, and it was the first thing I thought of as the web site for Healthé Trim popped up, and "Monique" began her speil...

Like OH MY GOD, wouldn't you just, like, love to get high school skinny again?

Uh... right, Monique.

First of all, I highly doubt you've ever had a weight problem. And secondly, how many years has it been since you've been in high school... like, uh, maybe three? Like whatever, Monique.

Thankfully, I was able to turn Monique "off", and have a closer look at Healthé Trim in peace and quiet. On the face of things, Healthé Trim seems like a winner. Although it makes the usual outlandish claims—that it will help you lose weight fast, curb your appetite, boost your metabolism while providing a long lasting boost of energy—its effectiveness appears to be backed by both a clinical study and a bona fide medical doctor's recommendation.

Let's take a closer look at the study...

To begin with, this study does not appear to be published in any journal that I could find.

So as far as I can tell it is not a peer-reviewed, published study.

What's the significance of this?

Well, when the people who have the most to gain financially from a positive outcome of a study are the same ones who are conducting it, it pays to be skeptical.

It doesn't necessarily negate the results, but until the study's methodology has been critiqued by credible professionals, it has minimal value indeed.

Secondly, what study parameters are revealed indicate this is a very "loose" study indeed. For example, study participants were asked not to change their daily eating regimen. What this essentially does is put every single person into their own unique study group, since each individual is going to be consuming a different number of calories each day.

Some people will eat more (or less) than others. Subconsciously, some may see the fact that they are taking a supplement as a reason to eat less. Others may see the pill as a license to eat more. And thus, it makes it very, very difficult to attribute any real value to the supplement since there are too many variables present to make a conclusive statement about its effectiveness.

And what about the "doctor" recommendation also so highly touted?

It appears that Dr. Michael Carroll is an Atlanta-based immunologist who wrote a diet book back in 1996 called "Be Fat Free Forever." According to the Healthé Trim web site, a friend introduced him to the product after losing "25 lbs. in 4 weeks" and now he's an avid fan, prescribing it regularly in his weight loss clinic. I'll let Dr. Carroll take it from there...

"... HealtheTrim is made in a pharmaceutical grade facility to ensure purity and quality control.  Each of the ingredients in HealtheTrim had individual research backing up their individual claims concerning their various biological activities.  What impressed me the most was the formulators of HealtheTrim not only chose the most appropriate ingredients to get the results they were looking for, but they created an effective blend or mix taking several years of testing before making the product available to the public. This was the confirmation I needed to begin using it with my patients in my weight management clinics."

Sorry doctor, but I'd like to take issue with you on a few points...

"Each of the ingredients in HealtheTrim had individual research backing up their individual claims concerning their various biological activities."

Really? It seems you and I must be looking at different versions of Healthé Trim then. For instance, where's the peer reviewed, published data that validates hoodia's ability to curb appetite and enhance weight loss? That pyruvate, in the dosage provided in this product, enhances weight loss, decreases appetite and increases energy? Some of the latest data I have seen isn't particularly positive. And that's at a 2,000 mg dosage! And what about chromium? It's hardly a weight loss miracle.

Next, this statement just doesn't pass the smell test...

"...the formulators of HealtheTrim not only chose the most appropriate ingredients to get the results they were looking for, but they created an effective blend or mix taking several years of testing before making the product available to the public."

You're telling me that instead of getting this product to the market immediately and starting to make money, the makers of Healthé Trim spent a couple of years piddling around testing the product—when they are not obligated by law to prove their product works as claimed? Even in-house studies are prohibitively expensive, and no one—short of the big drug companies—could afford to spend years running tests, reformulating, and testing again. And if they were really serious about demonstrating their product worked, they wouldn't have used such loose study parameters in the one so prominently presented on the sales page (as discussed above).

Sorry, but I don't buy it.

Before I even begin dissecting the ingredients, let's address another major problem. There are 16 ingredients in this formula. This might sound impressive, but here's the issue; just like pharmaceutical drugs, the "natural herbal" ingredients in weight loss products must be present in an appropriate dosage to have any effect. The makers of Healthé Trim are not revealing either the amount of total ingredients in the formula, or the amount of each individual ingredient (or even to what extent each ingredient is standardized, if it is at all).

Thus, it's impossible to effectively assess the impact of each ingredient on the formula. However, some basics logistics can tell us a lot. For example, the largest capsule size generally used by retailers and well-tolerated by consumers is "00".

The exact amount of ingredient such a capsule can contain depends on the density of the powdered ingredient, but a good general number is 650 mg.

So the greatest amount of active ingredient we can expect from this product is in the 1300 mg range (from a 2-cap dose).

Unfortunately, that means that the majority of the ingredients will only be present as "label dressing" (i.e., they make the label look impressive, but they do nothing for the effectiveness of the formula).

With that out of the way, let's have a look at the formula...

1) Resveratrol: A powerful antioxidant with possible anti-aging effects. From our review...

"While resveratrol shows a great deal of promise, questions remain about its utility in humans, as oral bioavailability is low and human clinical data is still lacking...pilot studies are just beginning."

2) Chromium picolinate: A trace mineral that plays an important role in proper insulin function, clincal data shows chromium to have minimal, if any effect on weight loss.

3) Green tea leaf extract: There's no doubt green tea is one of the no-brainer ingredients that shows some real promise for dieters. It is, of course, if it's present in a strong enough dose, and standardized for the appropriate catechins. Is it in this case? Your guess is as good as mine.

4) Hoodia gordonii: Despite all the hoopla about hoodia, the P57 molecule, and its amazing appetite suppressing qualities, no published clinical data validates this ingredients effects. Additionally, there are some real problems with supply and demand that suggest most hoodia products are counterfeit. Add the fact that Unilever curtailed its development of a hoodia product in 2008, and you've got to be skeptical. See the full hoodia review for complete details.

5) Caralluma fimbriata: An Indian cactus, there is a small amount of clinical data showing that 1,000 mg of Caralluma taken once a day for 60 days can suppress appetite and reduce weight circumference. It's a bit hard to believe there's a 1,000 mg of ingredient here, considering a 2 capsule dose is likely to only deliver 1300 mg or so, and there's 15 other ingredients in this formula.

6) Coix seed: Also known as Job's tears and used in traditional Chinese medicine for ages there is some early evidence this annual plant may have cancer fighting characteristics. More importantly for our purposes, a coix seed extract has been shown to have the ability to inhibit fatty acid synthase in rats.

Fatty acid synthase is an enzymatic system that is involved in the process of turning carbohydrates into fat. Early animal studies suggest the inhibition of fatty acid synthase can lead to dramatic weight loss.

7) Poria cocos: A fungus used in traditional Chinese medicine, there is some evidence this ingredient may have anti-cancer benefits and may also act as an anti-inflammatory. Nonetheless, very little western research has been performed on Poria cocus.

8) Cassia seed: Probably referring here to Cassia nomame, since it is often included in weight loss products for its "ability" to inhibit the enzyme lipase which is required for the break down and deposit of fat. However, there's very little clinical evidence to validate these claims. Check out this excerpt from this Pubmed abstract on "Nutraceutical resources for diabetes prevention"...

"There does not appear to be a natural lipase inhibitor functionally equivalent to orlistat, although there are poorly documented claims for Cassia nomame extracts." (Med Hypotheses. 2005;64(1):151-8.)

9) Lotus leaf: Um... when you're eating Dim sum, these are used to roll up your "sticky rice." Can't see any other good reason for this to be included here.

10) Water plantain: Also known as Alisma, this ingredient is likely included here for its diuretic action.

11) Cumquat: Kumquats are small fruit bearing trees. The citrus fruit looks similar to an orange, but is much smaller and more oval in shape. This is a perfect ingredient to further illustrate the labeling issues with this product. For instance, the peel of the fruit is a rich source of essential oil, which contains numerous constituents. What element of kumquat is this formula standardized for? Is it a fruit extract? A peel? An oil? Who knows?

12) Methionine: This ingredient aids in fat metabolism and acts as an antioxidant.

13) Mulberry leaf: There is some evidence mulberry leaf may be helpful in the treatment of diabetes.

14) Gymnema sylvestre: a plant native to India, there is some evidence it can inhibit glucose uptake in the small intestine as well as showing potential anti-diabetic effects—at doses much higher than present in this product, of course.

15) Eleutherococus senticoccus: Also known as Siberian ginseng, this herb is known as an adaptogen (similar to ginseng). However, it is an unrelated species—and not similar to either Asian or American ginseng.

16) Pyruvate: A "gateway" compound in a process called the "Krebs" cycle (the "Krebs" cycle is the intercellular process in which glucose (sugar derived from carbohydrates), is converted into energy). There is some evidence it helps with weight loss, but only at an extremely high dose (the aforementioned study used 22-44 grams of pyruvate).

In addition, Healthé Trim contains as undisclosed amount of unidentified "trace" minerals.

After reviewing the mass of ingredients in this formula, I hope the main issues previously discussed "pop out" at you...

For many of the ingredients, there's little or no clinical evidence validating the claimed weight loss effects. Some ingredients, although interesting, seem to be added for impact rather than effect. It's not revealed how much of any of the ingredients is included in the formula, nor what they are standardized for, if they are at all. Because of the logistics of serving size, most ingredients are likely to be under-dosed.

Despite the clinical study and "doctor's recommendation" the onus is on the makers of Healthé Trim to step up to the plate and provide this information to you, the consumer. They haven't done so, and that, in my opinion, is a red flag worthy of some attention.

That said, this product is backed by a guarantee...

"If you are not fully satisfied with any HealthyLife Sciences product, you may return your bottle within 30 days of delivery for a full refund, less shipping costs.  All bottles purchased must be returned.  Refunds will not be given on reorders of the same product.  If multiple bottles are purchased, only unopened bottles will be refunded.  Each customer allowed only one refund."

... which on the face of it, eliminates the risk from your purchase. IF they honor their guarantee and don't make you jump through hoops to receive a refund. That said, I'd love to hear from you. Have you used Healthé Trim? Did you request a refund? Were you refunded promptly and cheerfully? Let us know...

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Review: Bob Harper's Smart Weight Loss Fat Burner

Klick-ka-ching!

Money, no doubt, is the #1 motivating factor for the release of Bob Harper's Smart Weight Loss fat burner. Bob Harper, of course, is a personal trainer made popular by the T.V. show, "The Biggest Loser" (Jillian Michaels, another trainer from the show, also has her own line of supplements; we've reviewed both her fat burner and her "calorie control" products).

On the face of it, you'd think supplementing with weight loss and diet pills run contrary to the message touted by both Michaels and Harper—that good diet and nutrition coupled with a smart exercise plan are the key to long term, sustainable weight loss. Hard to blame them for changing their tune though; very few of us would be able to turn up our noses at the sort of money they're no doubt getting for allowing their names to be associated with the products in question.

Not all our visitors were particularly pleased with Jillian's apparent willingness to "sell out" and endorse a diet pill, and had absolutely no problems saying so.

With that said, what's the deal with Bob Harper's Smart Weight Loss fat burner? Is it any good? Does it work?

Well, first of all let's point out the obvious; Mr Harper might be a great trainer, motivator and life coach, but he's not in the business of formulating supplements. Someone else has done that, and he's leant his name to it, most likely in exchange for a couple of wheel-barrows full of money.

That said, he may have been "sold" on the product because of the "clinically-proven" weight loss ingredients and the positive clinical studies that were performed on the "key" ingredients.

Of course, we know the term "clinically proven" means next to nothing in the supplement industry; just because something produces measurable and statistically significant results in a study doesn't mean it's going to do anything for your weight loss success.

Like Elissa has said; "often, it's like getting a $50 discount on a Cadillac... measurable, but overall it hardly makes a difference.

But what about the clinical studies?

According to the product advertising...

"In study one, a 12-week third-party, randomized, double-blind, placebo-controlled clinical study, test subjects using the key ingredients (TrimSmart™: Frauenmantle extract, Wild olive extract, Cormino extract, Horsemint extract) in Bob Harper's Smart Weight Loss Formula lost an average of 20.94 lbs. versus the placebo group, who lost an average of 1.70 lbs. Both groups followed a calorie-reduced diet."

And...

"In study two, an 8-week randomized, double-blind, placebo-controlled clinical study funded by the makers of Bob Harper's Smart Weight Loss Formula, test subjects using the same key ingredients lost an average of 16.50 lbs vs 1.73 lbs. for the placebo group. Both groups followed a calorie-reduced diet."

Sounds pretty good, right?

On the surface, sure. But if you do a little digging you'll discover a few problems...

First of all, the 4 ingredients referenced in the first study are the exact same ones used in the newest Hydroxycut Pro series supplements and the exact same series of statements used to validate the claims made for those products.

The only difference is the way they are labeled.

On the Hydroxycut label, these 4 ingredients are labeled as "Alchemilla vulgaris extract, Olea europaea extract, Cuminum cyminum extract, and Mentha longifolia extract." If you didn't know better you might assume these are two different formulas but they are not; these are different names for the same compounds.

That in itself is misleading. The only reason why these are labeled differently is so that it's not immediately obvious these are near-identical products.

So the statement I read in the advertising—attributed to Bob himself...

"That's why I helped create this Smart Weight Loss Formula - with clinically proven key weight-loss ingredients, plus a naturally sourced energy boost to get the most out of your busy lifestyle!"

... is complete and utter nonsense. This isn't a unique and powerful formula created by Bob, it's a simple rehash of an already existing product.

In all likelihood, Bob Harper's Smart Weight Loss Formula is produced by Iovate, which is the same company that manufactures all the Hydroxycut products.

So that's problem #1; there's absolutely nothing unique or special about this formula.

What's problem #2?

Well, the results attained by either study can hardly be described as "earth shattering";1.75 lbs/week in the first and just over 2 lbs/week in the second.

This is well within the realms of what you can reasonably expect to achieve on a smart diet and exercise program.

And problem #3?

Neither highly touted study is readily accessible for viewing. One doesn't seem to be available anywhere, but the other does appears in the Open Complimentary Medical Journal, although it did take some time to dig it up. Remember, it's up to the retailer to ensure the studies they reference are available for review.

Why?

Because there's not a lot of difference between an unpublished study that we can't actually view anywhere, and no study at all. It's one thing to say you have clinical studies to prove something works, but if you don't let anyone see them to verify that your methodologies are sound and your results genuine, it doesn't mean much.

Given the unregulated nature of the supplement industry and the willingness of retailers to push the limits, any study that you can't find in the PubMed database must be immediately viewed with skepticism, unless you have some valid reason to believe otherwise.

And, when you actually look closely at the study that is published, you'll quickly understand why it is not something eagerly referenced by the retailers of either the Hydroxycut or Smart Weight Loss products. There are some serious problems with the methodologies and after reviewing the document, it's hard to allot a lot of credence to results.

Let's take a look...

1) The caloric intake of the participants was not restricted or monitored.

The product advertising claims participants were following a calorie restricted diet. Here's where we get into semantics; it's true that participants were asked to restrict their meals to three per day. However, depending on their food choices, this may or not actually qualify as a "calorie restricted diet" as we understand it to mean; consuming fewer calories than one requires.

And, since the calorie value of meals can vary dramatically depending on your food choices, this essentially places each individual into their own unique study group—as no two participants will consume exactly the same amount of calories.

Think about it: if you know participants are still over-consuming calories in a significant amount, yet losing weight, that makes these ingredients significantly more valuable. If participants are under-consuming calories, that undermines the study results, does it not?

Fact is, if you don't know how many calories your audience is consuming, it's impossible to accurately attribute any success or failure to a series of ingredients.

2) The study was not performed on either Bob Harper's Smart Weight Loss fat burner or any of the Hydroxycut Pro series products.

Nope, the study was performed on a product called "Weighlevel."

Big deal, right?

Wrong.

These aren't the same products, and you cannot attribute results obtained in one study to another product. Especially when that product (Bob Harper's Smart Weight Loss) contains a proprietary blend, which means we can't confirm the dosage in the product conforms to the dosage of the ingredients used in the study.

3) The study is published in an obscure journal and 5 of the 6 co-authors have a financial conflict of interest.

If you check the study, you'll see that one co-author, Eli Kassis, is directly affiliated with Sprunk-Jansen (the manufacturer of the WeighLevel product).

And here, the plot thickens; Sprunk-Jansen is a partner of the Antaki Center For Herbal Medicine and has "exclusive rights" to world-wide distribution of the products the Center develops. And—wouldn't you just know it—4 other co-authors are directly affiliated with the Antaki Center for Herbal Medicine.

Whoops.

It's hardly "independent research" when 5 of the 6 study authors have a vested interest in a positive study result.

And to make matters worse, neither Elissa or I have ever heard of "The Open Complementary Medicine Journal". If nothing else, it's certainly not a well known, often referenced journal.

So let's sum the study issues up...

The study hardly qualifies as "independent research" considering the financial conflict of interest exhibited by the majority of study authors. The study was not performed on Bob Harper's Smart Weight Loss fat burner, nor is there any way for us to determine whether or not Mr. Harper's product contains an adequate amount of the 4 core ingredients.The study's methodologies can hardly be described as "rigorous.".

OK, but what about the remaining ingredients? Well, in addition to the highly touted quartet (of Frauenmantle extract, Wild olive extract, Cormino extract, Horsemint extract) there's that...

"... naturally sourced energy boost to get the most out of your busy lifestyle!"

... that Bob brags about. Of course, we like to call it what it really is; caffeine. The same stimulant you get from your coffee, tea, lattes, colas, chocolate and so on. And the same stimulant included in just about every fat burner under the sun. Bob Harper's Smart Weight Loss fat burner contains a whopping dose; 180 mg in a two capsule serving.

At a full day's 6-cap dosage, you'll be getting 540 mg of caffeine, which is slightly less than the equivalent of 6 cups of coffee's worth of caffeine. That definitely means you'll get plenty of "energy" from this product. It also means it's not ideal for anyone with high blood pressure or heart troubles.

Of course, caffeine is a well-established thermogenic and does deliver mild weight loss effects (see Am J Clin Nutr. 1989 Jan;49(1):44-50, Am J Clin Nutr. 1980 May;33(5):989-97).

If there's a downside to caffeine is that's it's really cheap; you can buy a whole bottle of 200 mg tabs for $5. So its inclusion here does not justify a purchase.

The Smart Weight Loss product also contains a smattering of both goji berry and pomegranate; nether of which can be included in a dose potent enough to elicit any effect. They are here for label decoration only.

So where does that leave us?

Obviously, we're certainly not overwhelmed with the formula, but we're even less impressed by the price of Bob's product; 72 caps will set you back $24.99 at GNC.

Taken at the recommended dosage (days 1-3, 1 cap 3 X daily, days 4 on, 2 caps 3 X daily) this will last less than two weeks. If you really feel you have to experiment with his formula, you can buy a month's worth of the original Weighlevel formula (the product the referenced studies was actually performed on) for just over $21 at MyVitanet.

Stack each serving with a 200 mg caffeine tab (you can buy 100 tabs (enough for a month) for less than $5 at a reputable online retailer like BodyBuilding.com) and you will essentially duplicate this formula for less than half the cost.

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Review: hCG Diet Drops For Weight Loss

Before discussing the validity of hCG diet drops for weight loss, let's start with a bit of background information...

Although almost 50 years old, the hCG diet protocol triumphed by Dr. Simeons has experienced a resurgence in popularity of late, possibly due to the success of such books as "The Weight Loss Cure They Don't Want You To Know About" by Kevin Trudeau. Prominent media coverage of the diet hasn't hurt either.

Although I've covered this more thoroughly in the hCG diet review, this protocol refers to a weight loss regimen that involves...

Daily injections of hCG (or human chorionic gonadotropin) A restrictive VLCD (Very Low Calorie Diet; in the case of the Simeons protocol diet is restricted to 500 calories daily). Regular follow ups with a monitoring physician or professional (since hCG genuine is a prescription drug, hCG must be administered by a qualified professional). This introduces an element of "accountability" into the diet, which can help with its success; if you have to answer to someone else other than yourself, you make a greater effort.

There's a real problem with the hCG diet protocol, however. Although an early study (the Asher-Harper study, performed in 1973) found the hCG diet protocol to be helpful, all other follow up studies have shown it does not outperform a placebo (a placebo, in this case, includes a VLCD and regular monitoring, but no hCG injections).

This study, for example, sought to duplicate the results of the Asher-Harper study, but in the end concluded...

"hCG does not appear to enhance the effectiveness of a rigidly imposed regimen for weight reduction."

A more recent meta analysis published in the British Journal of Clinical Pharmacology concluded...

"...there is no scientific evidence that HCG is effective in the treatment of obesity; it does not bring about weight-loss of fat-redistribution, nor does it reduce hunger or induce a feeling of well-being."

So what's all this got to do with hCG diet drops for weight loss?

Well, here's the thing...

Genuine hCG is a prescription drug. It needs to be prescribed by, and administered by a physician.

If you've seen hCG drops or homeopathic hCG drops for sale online, rest assured, these do not contain prescription hCG. Homeopathic preparations are extremely diluted—often to the point where the active ingredient can no longer be detected using conventional technologies. And there's absolutely ZERO evidence they work.

Numerous scientific studies (see Br J Clin Pharmacol. 2002 December; 54(6): 577–582 and Mayo Clin Proc. 2007 Jan;82(1):69-75 as examples) confirm this; homeopathic preparations are no more effective than a placebo (for more on homeopathy, see CBC's MarketPlace investigation).

Even if you wanted to argue the merit of homeopathic preparations, there's no evidence extremely diluted hCG preparations would have the same effect as the prescription drug administered in a dosage of 125-200 iu daily; a very obviously "un-diluted" dosage.

And remember; if these products actually contained hCG in any significant amount, you'd need a prescription to get it.

Bottom line?

To my knowledge, hCG cannot by administered effectively by sublingual means, nor is there a genuine, prescription alternative to injections.

Even worse, hCG drops might very well be the "ultimate scam."

Why is that?

Because when administered alongside the Simeons diet protocol and the VLCD that accompanies it, homeopathic hCG drops will work just as well as prescription hCG.

That is, they won't "work" at all.

Oh, you'll lose weight alright. Probably lots. After all, Very Low Calorie Diets DO work. But your weight loss will have absolutely nothing to do with the hCG drops you're consuming and everything to do with the fact that you're consuming minimal calories.

Additionally, the FDA has spoken out on hCG drops, calling them "illegal."

Now we realize what we're telling you here may run contrary to what you've read elsewhere online.

The fact is, many of the folks who are going on about the benefits of hCG drops versus injections have a financial conflict of interest—they earn commissions on referred sales (go to Google and perform a search for "hCG drops + affiliate program" (without quotes) and see what you find). That calls the credibility of their recommendation into question.

The fact is, hCG drops may not require a prescription, they may be cheaper and more convenient than injections, but there's no evidence they do anything.

Buyer beware.

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CAUTION: Are You Losing Fat The Right Way?

Do you feel like you have been mislead on how to lose fat? Most people want to lose fat fast, but how much is the RIGHT amount of fat to lose at a time and most importantly what are the best ways to lose fat? Let's talk first about what's actually a safe amount of fat to lose at a time and what it's going to take. Then I am going to break down losing fat in the 3 most common areas I get asked about.

It's not uncommon for the body to be able to lose fat fast, and when I say that I mean up to 1.5lbs of unwanted body fat per day. That is of course if you have that much fat to lose. From my experience fat ends up being the result of one problem with the body and that is the over acidification of the body. Your body has a natural pH of 7.365 and over the course of time from stress,diets,beverages,and lifestyle we gradually turn our body into fat storing and producing bodies. Most people want to lose belly fat, now why would that be? The reason our bodies produce fat is to protect us from the acidic nature of our body. The body produces fat to store toxins AWAY from vital organs and weaker areas of the body, which is why most people are confused when it comes to losing fat. I just identified the problem for you. How about the solution.

Clean your blood and balance your bodies pH BACK to a normal state. You can take VERY simple steps to do this by first starting to drink at least half your body weight in ounces of distilled or purified reverse osmosis water daily. Limit animal sources of protein other than fatty fish such as tuna,trout,or salmon. Other animal based sources of protein contain higher contents of acid. Put more greens into your diet such as spinach, avocado,broccoli, asparagus, brussels sprouts, kale, etc. Through all my research on clients most people start with about a 20% alkaline diet and an 80% acidic diet which would explain why one would have some unwanted body fat.

I am going to provide you with an article I just wrote on what you can do to target three of the most common areas people want to lose fat. How to lose fat on your thighs, how to lose belly fat, and how to lose body fat percentage overall. I can understand that you might not enjoy how you look or feel right now, but rest assured there is a solution to the problem. Once you learn the truths about weight loss and how to keep unwanted pounds off permanently you will have nothing to worry about. That's my goal, is to show YOU exactly what it's going to take without being drastic or going way out of your comfort zone. Just understand, that in order to get to a place you have never been you are going to have to do things you have never done.

Make sure you take the information below seriously if you want help to lose fat fast.

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Beverly International Lean Out Fat Burner Review:

Beverly International claims their Lean Out fat burner is the "optimum lipotropic formula in the world," and that it should be in everyone's diet. No surprise there. Retailers don't make money when their products gather dust; ergo, almost every weight loss product in the world boasts the most amazing, revolutionary, ground-breaking formula (and so on and so on and so on) and you must have it in your possession.

That said, what's the story with Beverly International's Lean Out?

First and foremost, this is an "old-school" formula. Lipotropics (ingredients that facilitate the conversion of fats into other useful products) have been used in weight loss supplements for years (to little effect) and the other foundational ingredients of this formula —carnitine and chromium—are no strangers either.

It's rare you see them trumped up to the extreme anymore, simply because the existing clinical data doesn't support such claims, and it's easy to refute them.

With that said, let's take a closer look at the formula. In addition to a couple of B-Vitamins (B12, Biotin) Lean Out contains...

1) Inositol (1000 mg): A well known lipotropic, inositol is involved in nutrient transfer at the cellular level. It also facilitates communication between nerve cells and helps to transport fats throughout the body.

2) Choline Bitartrate (1000 mg): Choline serves a number of vital functions, including maintaining the structure/function of cell membranes, normalizing homocysteine levels (via a metabolite, betaine), and serving as a precursor for acetylcholine, a neurotransmitter important to learning and memory. It plays a vital role in maintaining proper fat metabolism by the liver.

In one study, it was shown that choline supplementation reversed fatty liver disease—something that can occur when the liver has an inability to process fats properly. Other studies show it has no particular effects on exercise performance.

3) Chromium (200 mcg Chromium Picolinate): Because chromium plays a vital role in insulin function, it's a smart addition to any weight loss supplement. Clinical evidence documenting chromium's role in weight loss is contradictory. Some show a modest effect, some show no effect, and others even call the robustness and methodology of the studies into question.

4) DL-Methionine (1000 mg): This ingredient aids in fat metabolism and acts as an antioxidant.

5) L-Carnitine (600 mg): The advertising for Lean Out makes much out of Carnitine's role in fat burning, due to its ability to faciliate the transport of fatty acids to the mitochondria of the cell (the mitochondria is the cell's "furnace"). The problem with L-carnitine is that while it looks good in theory, clinical evidence validating its effectiveness is contradictory and inconclusive.

Additionally, any positive effect is only realized with a very large, multi-gram dosage. Rather bafflingly, the Lean Out advertising copy notes this—something I found pretty ironic, considering their own product delivers approximately a mere one third to one-sixth of an "effective" dosage in a 4-tablet daily serving. By the retailer's own admission then, this product contains nowhere near an effective dose of carnitine. An odd advertising strategy, to say the least.

6) Betaine HCL (100 mg): A naturally-occurring nutrient/metabolite with therapeutic applications; it can be used to treat non-alcoholic fatty liver disease, for instance.

7) Coenzyme Q10 (10 mg): A potent antioxidant, Coenzyme Q10 has been used experimentally to treat mitochondrial diseases.

So there you have it. Beverly International's Lean Out in a nutshell.

In theory, taking supplemental lipotropics ensures you have plenty of the raw materials on hand to properly metabolize fat and improve your body's efficiency of such.

In practice though, I've never read anything—either clinical or anecdotal—to suggest supplementation provides any more than the subtlest of effects.

And that makes sense, since anyone focused on eating properly is likely to be obtaining more than adequate amounts of all lipotropics directly from the diet.

That doesn't leave Lean Out with much else to offer; a sprinkling of carnitine, some chromium, a few B vitamins, and a few milligrams of betaine and coenzyme Q10. And at $28 for a month's supply, it's a bit difficult to recommend just as a simple experiment.

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Chili Burn Review: Can Chili Peppers Aid Weight Loss?

Chili Burn is a weight loss supplement that contains—not surprisingly—chili pepper, along with a handful of other ingredients. These include green tea, dill, peppermint and ginger root. The name "Chili Burn" seems a bit of a stretch considering just how little chili pepper this product contains—a mere 24 mg. Green tea, on the other hand, is present at a significantly larger amount; 972 mg per 2 capsule serving.

But let's leave all that aside for a moment, and concentrate on the ingredient that gives this product its name; chili pepper.

Can chili peppers really help with weight loss?

It seems that they can. Let me explain...

Chili peppers contain naturally occurring substances called capsanoids, and two of those—capsaicin and dihydrocapsaicin—are the ones of greatest interest to the folks who put weight loss products like this together. In the case of Chili Burn, capsaicin is the active component the chili pepper component of the formula is standardized for, although just how much is not revealed in any of the product literature I reviewed.

Dihydrocapsaicin also has "clinically demonstrated" weight loss effects, although its effects can hardly be described as dramatic.

Animal studies suggest capsaicin supplementation has weight loss benefits, and human studies also show benefits. This study concluded...

"In the short term, both oral and gastrointestinal exposure to capsaicin increased satiety and reduced energy and fat intake; the stronger reduction with oral exposure suggests a sensory effect of capsaicin."

Or in other words, a properly standardized red pepper supplement (this one used in the referenced study contained 900 mg of red pepper standardized for .25% capsaicin) may help you feel full for longer, and actually reduce the amount of food you consume at a meal.

These aren't the only studies showing red pepper to have both slight metabolism-elevating, satiating or appetite suppressing effects. There are plenty (you can see examples here and here).

The problem with these studies is that they showed a huge amount of chili pepper was required to achieve the desired effect; 6-10 grams was used in the studies I referenced a moment ago. And, further studies suggest that some benefits are dependent on a very high dose...

"...the maximum tolerable dose is necessary to have a suppressive effect of red pepper on fat intake."

Essentially, what this means is that chili pepper's weight loss effects are dose dependent. In other words, to get the greatest benefit from it, you need to take a lot.

And Chili Burn does not contain a lot—it contains 24 mg, standardized for an indeterminate amount of capsaicin.

That makes it impossible to assess the true value of chili pepper to this formula.

What about the rest of the formula?

Well, when standardized appropriately, green tea has demonstrated benefits for weight loss—although its effects are usually exaggerated by retailers (to put green tea's effects into context, read "How Much Weight Can I Lose With Green Tea?). Chili Burn contains plenty of green tea and it is standardized for the appropriate catechin, but we don't know the potency of the extract... that is not revealed.

Other ingredients—dill, peppermint, ginger root—are included in doses so middling as to serve as little more than "label dressing."

So what's the bottom line on Chili Burn?

While the product isn't expensive, there's very little here to justify a purchase, especially given the ambiguity of the product's labeling. If New Nordic were serious about delivering real value, they'd be up front about their standardized extracts.

I've seen several review sites give this product a poor rating for no other reason than to provide a link to an alternative product which they promote and earn a commission on. Very often, this product is Capsiplex or Capsimax. Don't be fooled; neither of these products is a weight loss miracle either, and the reality of chili pepper's weight loss effects is not any less applicable with a different product.

To read the Capsiplex review, click here!

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How Much Weight Can I Lose With Green Tea?

If you're reading this, it's probably because you've read—or heard—how great green tea is for weight loss, and you're wondering...

"Just how much weight can I really lose with green tea?"

This is a very good question to be asking.

You see, supplement retailers—the folks so eager to sell you the green tea diet pills that will "melt the fat" from your body—are more than happy to cite various "studies" that supposedly validate this ingredient's amazing weight loss benefits. What they do not do, for reasons that will become obvious in a moment, is explain them in context.

Because if they did, it would be much more difficult to get you to hand over your credit card.

For example, you may be aware that a bona fide, published, peer-reviewed clinical study clearly demonstrates consuming green tea supplements can elevate the metabolism. Most retailers are happy to reference this study, which was published in the American Journal of Clinical Nutrition.

But what they do not do, is explain the study clearly or link to the study abstract so you can view the results for yourself (hang in there; I know you still want to know how much weight you can lose with green tea, but this is important!).

So let's look at this study more closely.

If you put aside all the technical jargon and garble-dee-gook, what it boils down to is this; a green tea supplement standardized for 50 mg caffeine and 90 mg EGCG taken 3 times per day boosted the metabolism by 4%.

What's that mean, really?

Well, if you're a 140 lbs. woman whose caloric requirements are 1500 calories per day, a 4% boost in metabolism equates to 60 calories. If you're a 185 lbs. guy whose caloric requirements are 2500 calories per day, a 4% increase equates to 100 calories.

With that in mind, let's get back to the question, "how much weight can I really lose with green tea?"

A single pound of fat equates to approximately 3500 calories. If our 185 lbs. guy consumed only the calories he required (neither over or under-consuming them) it would take 35 days of supplementing with an appropriately dosed green tea supplement to lose the caloric equivalent of a pound of fat.

Assuming the same thing for our 140 lbs. woman, she would need to supplement for 58 days. (This is, of course, a vastly simplified explanation of how weight loss actually works, but I've presented it this way to provide you with some much needed context).

Obviously, green tea helps a little, but it's not particularly helpful if you have 20 or 30 pounds to lose.

And it's certainly no miracle pill.

But that's not to say that you shouldn't consider drinking green tea or taking a supplement—the benefits it offers are extensive, regardless of its weight loss effectiveness.

Additionally, preliminary studies suggest it may inhibit the action of several enzymes critical to the metabolism of carbohydrates, leading to a "carb blocking" effect. This could mean green tea's weight loss effects may be more dramatic than previously thought (see the complete green tea review for more details).

If you still think an experiment is in order, don't buy into the hype of over-priced products. For slightly over $10 you can buy an extremely potent product at a reputable online retailer. You may want to stack this product with half a caffeine pill; caffeine and EGCG are the two most critical elements of this stack and the aforementioned product does not appear to be standardized for caffeine.

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Cellucor D4 Thermal Shock Fat Burner Review

Cellucor D4 Thermal Shock Fat Burner ReviewøSEARCH SITEe.g. Zantrex 3, Relacore, etc.

Home/Fat BurnersRecommendationsFunctional FoodsBodyBuildingVitamins/MineralsDiet PillsThe BlogArticlesDietsGlossary Cellucor D4 Thermal Shock Fat Burner Review Share|

Cellucor's D4 Thermal Shock fat burner claims to be able to...

Attack deep fat deposits Skyrocket caloric burn Provide explosive energy Suppress appetite Improve mental focus

Since the Cellucor brand has the reputation for selling higher-end, more costly—and allegedly—more effective products, we thought it was high time we took a closer look at one of their offerings, putting the ingredients profile under the microscope.

So, what's in D4 Thermal Shock? Two capsules boast a 1,093 mg blend of the following 10 ingredients...

1) Emblic Myrobalan Extract: Also known as Amla and Indian gooseberry, and incorrectly labeled as "embelic myrobalan extract" on various retailers' web sites, this is one of the ingredients that Cellucor claims to act as a "beta-2 adrenergic agonist" in their formula. This, thanks to one of its active compounds—"phyllemblin."

Unfortunately I was unable to either confirm or deny this claim, despite some fairly serious digging. When conferring with our scientific and technical advisor Elissa about this ingredient, she forwarded me this document, noting...

"This "sort of" confirms this claim, although it's vague about whether any human research has been done. But there are no references in this document, nor are there any relevant abstracts to be found in PubMed. So either this claim is based on unpublished research; research published in very obscure Asian journals; "in-house" stuff prepared by whatever company they sourced the ingredient from; or stuff published prior to - say - 1960 (it's much harder to find older abstracts/papers online)."

For the record, Amla is an Ayurvedic treatment for asthma and cough, so it's not impossible that it contains some sort of beta-adrenergic activity.

However, even if we assume that Cellucor is right about phyllemblin being a potent beta-2 adrenergic agonist, we are still faced with a couple of problems...

How much phyllemblin is actually in the so-called emblic myrobalan extract? Is it orally active? Is the emblic myrobalan extract standardized for phyllemblin? Is it provided in an amount sufficient to produce the desired effects?

The onus is on Cellucor to address every one of these issues, and to date, they have not done so.

2) Caffeine: This ingredient has a well established record as a mild thermogenic, and does deliver mild weight loss results (see Am J Clin Nutr. 1989 Jan;49(1):44-50, Am J Clin Nutr. 1980 May;33(5):989-97). As such, it's an ingredient common to the majority of fat burners on the market. And of course, caffeine cheaply and effectively addresses the most common complaint of dieters; lack of energy.

However, D4 Thermal Shock contains a TON of caffeine—290 mg per two capsule serving. That's the equivalent to three cups of coffee's worth! As such, this is a product that is going to give you one heck of a boost. If you have a sensitivity to caffeine and/or stimulants you will probably want to start with 1 capsule 2 times per day to assess your tolerance to this product.

3) White willow bark: In the old days, white willow bark was used as the herbal form of salicin, and comprised the third element of the good old ephedra / caffeine / aspirin stack. In ephedra-free fat burners like this one, there is no evidence it offers any benefit, short of the anti-inflammatory effects inherent to salicin.

4) Octopamine HCL: This is the second ingredient touted by Cellucor to act as a beta-2 adrenergic agonist. Just for fun, I'm going to pull the definition for this directly from our glossary...

"A biogenic amine and constituent of Citrus aurantium (bitter orange). Octopamine is promoted as a fat loss agent, although there is only limited animal (and NO human) data to support this.  Any effects on fat loss are likely to be weak, as its oral bioavailability is low.

See David Tolson’s article, “Octopamine Science” for more information.

5) Yohimbine: The standardized extract of the bark of the African Yohimbe tree, there is some data showing yohimbine is a somewhat effective weight loss supplement (see Isr J Med Sci. 1991 Oct;27(10):550-6) likely because of its action as an alpha 2-receptor antagonist. Evidence also validates its "lipid-mobilizing action."

6) Evodiamine: A compound derived from the Chinese fruit Evodia Rutaecarpa. It's claimed to burn fat by increasing the body's production of heat, as well as reducing the body's ability to store fat.

Although a preliminary animal study shows promising results, to date there's no evidence showing evodiamine works in people.

7) Sclareolide: Also known as clary sage extract. Theoretically, sclareolide is a cAMP stimulator (as is forskohlin). cAMP is what is called a "cellular regulator." In other words, this compound is required to "spark" many intercellular processes. An increased concentration of cAMP can have such "total-body" effects as raised thyroid hormone levels and increased fat burning. While there is some evidence that forskohlin exhibits modest weight loss effects, no such evidence exists to validate such a claim for sclareolide.

The final 3 ingredients are included to address the "improve mental focus" claim...

8) Vinpocetine: Once again from our glossary...

"An alkaloid derived from periwinkle that affects cerebral blood flow, memory and learning. Vinpocetine is often added to pre-workout, stimulant blends designed to improve focus, concentration and training drive."

9) Passion Flower Extract: This herb demonstrates a mild sedative effect.

10) N-Acetyl-L-Tyrosine: An amino acid which happens to be the precursor of several important neurotransmitters (l-dopa, dopamine, norepinephrine, and epinephrine) which are important contributors to mood, cognitive performance, as well as combating stress. And yes, there is evidence that l-tyrosine has a positive effect on mood (see full tyrosine review for accompanying clinical references) and cognitive performance.

Unfortunately, these results were obtained with dosages that vastly exceed what is present in this formula. For example this study (which showed an improvement in cognitive function) was performed with 100 mg/kg tyrosine.

To put that in perspective a 200 lbs. man would need to take about 9 grams, or 9000 mg of tyrosine to obtain this effect.

If D4 Thermal Shock contained nothing but tyrosine, it would take 4 days worth of capsules (at the full 4 caps/day dose) to deliver an effective dose.

Although the "acetyl" version of tyrosine may (or may not) be somewhat more effective, there's certainly no reason to believe this ingredient serves nothing more than label dressing in this formula.

So there you have it—Cellucor's D4 Themal Shock.

As you can see, there are a few problems with this formula. For one, several of these ingredients appear to be included on the basis of mere speculation.

Others have little or only animal based clinical evidence to validate their effectiveness, and others... well, they're simply ordinary ingredients you can readily find in much cheaper products. You might enjoy the "blast" of energy D4 Thermal Shock Delivers, but you really don't need to spend $45 / bottle for it.

In my opinion, when you're paying nearly $72 for a month's worth of product, you have every right to expect Cellucor to "step up" with more than simple generalities and advertising "spiel". Cellucor needs to provide some evidence that highly touted ingredients like "emblic myrobalan extract" actually work as described.

That said, I'd love to hear from any of you who have used this product. What did you think? How did it work for you? Use the link below to leave your comments, and read existing user reviews...

 

Have you used D4 Thermal Shock? Share your
comments and read D4 Thermal Shock user reviews / testimonials, click here!

 

 

 

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What Are The Best Natural Appetite Suppressants?

If you're on the quest for the best natural appetite suppressant, you're not alone; a large percentage of dieters and our visitors have made it clear that such a supplement would be of great value to them.

That said, what are your options when it comes to natural appetite suppressants? As you'll see, there are plenty of supplements that are advertised as such, but relatively few that have a significant body of peer-reviewed, published clinical data behind them.

Let's take a look at some of the more commonly advertised appetite suppressants...

Description: A cactus native to South Africa, this protected species is "claimed" to be able to suppress the appetite thanks to the action of the novel P57 molecule.

Possible issues: Because hoodia is an endangered species that takes several years to grow to maturity, there is a great likelihood that the majority of hoodia products on the market don't contain any hoodia. According to Mike Adams of NewsTarget.com, up to 80% of the Hoodia sold on the market is counterfeit, with 60% of the products sold in the U.S. failing laboratory verification.

Study status: No peer-reviewed, published clinical data exists to demonstrate the appetite suppressing qualities of hoodia.

Interesting stuff: In December 2004, PhytoPharm teamed up with Unilever (who owns SlimFast, Knorr, and Hellman's, among other things), and committed to bringing the active P57 molecule to the market within 3 years.

At the end of 2008 (as announced in this document) Unilever terminated its relationship with PhytoPharm and the development of a hoodia-based weight loss product—making it even more difficult to believe that's there's any real merit to hoodia for weight loss.

Anecdotal reports: Some people report appetite suppression when using credible hoodia-based products. Our "in the trenches" product tester Amie experimented with hoodia and wrote about her experiences here! In short, she found that hoodia curbed her appetite significantly, but nevertheless, didn't end up losing weight.

Recommendation: Real, quality hoodia products (like the Hoodoba brand) are expensive and have little in the way of scientific evidence to validate their effectiveness. Is hoodia worth trying just to see?

It's a decision you have to make. It's certainly not your most cost effective option, and certainly not recommended if you're on a tight budget.

Description: Derived from citrus aurantium (also known as "bitter orange"), synephrine is a chemical "cousin" of ephedra. After the ephedra ban, it replaced the ephedra content of many popular weight loss supplements, on the assumption it would work in a similar manner.

Possible issues: Synephrine is often used in "stimulant free" weight loss formulas. This, despite evidence showing it is a stimulant, and does elevate both blood pressure and heart rate.

Study status: Clinical data shows synephrine demonstrates extremely modest benefits at best. One study concluded...

"There is little evidence that products containing C. aurantium are an effective aid to weight loss."

Anecdotal reports: Some users find synephrine is a helpful appetite suppressant.

Recommendation: Not exactly a winner, but it is cheap (around $14 at BodyBuilding.com for 180 caps, or a 2 months supply) if you'd like to experiment with it as an appetite suppressant.

Description: The popular name for a small Brazilian tree, Cordia salicifolia. It is marketed as a weight loss supplement and as an appetite suppressant.

Possible issues: N/A

Study status: No peer-reviewed, published clinical data exists to demonstrate the fat burning or appetite suppressing qualities of Cha de Bugre.

Anecdotal reports: Some users, including our own scientific and technical advisor Elissa, have found Cha de Bugre to exhibit moderate appetite suppressing characteristics.

Recommendation: Not much science supporting it, but cheap enough to experiment with (as little as $10 at iHerb.com - use the coupon code FAT259 to get $5 off your first order).

Description: Occasionally labeled as "konjac" or "amorphophallus konjac", glucomannan is an un-absorbable polysaccharide that is derived from the konjac root. In short, it is a source of fiber. There are many glucomannan based products on the market, including PGX Daily and Lipozene.

Possible issues: Glucomannan pills can occasionally get stuck in the esophagus and cause a blockage. One study bears this out, indicating that glucomannan-based supplements can pose a hazard for individuals with a history of upper gastrointestinal pathology.

Study status: There is some clinical data to validate glucommanan's ability to increase satiety, lower LDL cholesterol, blood lipid levels and blood sugar levels (especially in diabetics) and help with weight loss. See the full glucomannan review for accompanying clinical references.

Anecdotal reports: Some users find glucommanan helps them feel full longer, and eat less at mealtimes.

Recommendation: Cheap and worth a try (a 180-capsule bottle is just under $10 at BodyBuilding.com). If the capsules are too big for you, break them open and sprinkle them over your food.

Description: Native to India, this plant's leaves have been used as a traditional natural remedy for diabetes. In weight loss products, it's used to inhibit the ability to taste sweetness as well as the intestinal absorption of glucose. It may also have an "anti-diabetic" effect. Not a "true" appetite suppressant, but may help in this manner, if it does suppress sweetness.

Possible issues: N/A

Study status: There is a small body of preliminary evidence indicating gymnema may indeed provide benefits for dieters. One problem though; the majority of studies showing the inhibition of the ability to taste sweet or bitter were performed primarily on rats and mice (for more accompanying study references, please see the glossary listing).

Anecdotal reports: We have received no anecdotal reports on gymnema.

Recommendation: Up to you if you'd like to experiment. A 6-week supply is pretty reasonably priced (about $14 at a reputable online retailer like BodyBuilding.com).

Description: An Indian cactus marketed as an appetite suppressant.

Possible issues: N/A

Study status: One study validates caralluma's weight loss and appetite suppressing benefits, although they are relatively modest.

Anecdotal reports: Customer testimonials and feedback on Dex-C20 (a caralluma-based supplement) and Slimaluma® (the patented version of caralluma) is mixed; some folks found it helpful for appetite suppression, others found it did nothing.

Recommendation: It's cheap enough to experiment with (under $15 for 60 caps) should you think it is warranted. Try Now brand's SlimaLuma Plus (which also contains green tea extract and yerba mate) for two weeks and see if it helps.

Description: A highly nutritious protein derived from milk, and used by bodybuilders for its anti-catabolic properties.

Possible issues: Casein is potentially allergenic, although most milk allergies are formed during early childhood.

Study status: Casein protein offers numerous documented benefits (see the full review for accompanying clinical references) but nothing has been documented pertaining to appetite suppression or satiety.

Anecdotal reports: Because casein is a slow-digesting protein, some people find supplementing with a casein protein can help them feel full longer, thus reducing their appetite.

Recommendation: If you're already using a protein supplement, it might be worthwhile to switch to a quality casein based product. For individuals not supplementing with a protein powder, and have no interest in doing so, perhaps one of the other options on this page would be a better choice.

Palm/Oat Oil Blend (SlimShots)Description: A blend of oil derived from palm and oat sources, and served in small "shots" (the size of a disposable coffee creamer) retailers claim this special concoction can increase satiety and suppress appetite.

Possible issues: N/A

Study status: Yes, there are several studies that indicate this oil blend is helpful for appetite suppression and satiety (see the SlimShots review for accompanying clinical references), although not all studies are positive.

Interesting stuff: It's impossible to tell whether commercial palm/oat oil appetite suppressant products contain a potent enough dosage, or one that corresponds to the positive clinical studies referenced in the full SlimShots review.

Anecdotal reports: Mixed, but more negative than positive. Some of our visitors have found this product helpful, others not. Click here to read user reviews and testimonials on SlimShots!

Recommendation: Although some visitors have reported finding SlimShots and other similar products at bargain prices on occasion, they are generally a fairly expensive product. It's hard to make a recommendation when we're not convinced you'll receive much value for your dollar. Ultimately then, it's a decision you have to make.

Description: More commonly known as "Korean Pine Nut Oil", Pinnothin is advertised as an appetite suppressant (it is thought to stimulate several appetite suppressing hormones—cholecystokinin and glucagon-like peptide 1).

Possible issues: N/A

Study status: Very little published data exists for this ingredient, and what little there is (see Lipids Health Dis. 2008 Feb 28;7:6) demonstrated mediocre results at best. Our scientific and technical advisor Elissa summed it up best when she reported...

"The results are pretty underwhelming—2 g of Pinnothin taken 30 min before a buffet lunch reduced food intake by 9% - by weight in grams - and energy intake by 7%. The latter figure averaged to a whopping 50 calories."

Anecdotal reports: We have received no anecdotal reports on the appetite suppressing qualities of PinnoThin.

Recommendation: There's no reason to recommend experimenting with PinnoThin at this time.

Description: A supplement (called "sprinkles") that you "sprinkle" onto your meals, to increase satiety (the feeling of "fullness") and decrease appetite.

Possible issues: Purchasing Sensa from the official web site may add you to a recurring billing program, especially if you "try it free" (click here to watch our video of the "free trial scam").

Study status: Much ado is made on the official Sensa web site about the "clinically proven" status of the Tastants products. There are all sorts of problems with this, the most obvious one being that this was an in-house study that has never been published in a peer-reviewed journal. Please see the full Sensa Tastants review for a complete discussion of this issue.

Anecdotal reports: Mixed reviews on the products effectiveness, and plenty of billing issues.

Recommendation: There's no reason to recommend experimenting with Sensa Tastants at this time.

 

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ErgoLean Amp 2 Review: Weightloss And Energy?

ErgoLean's Amp 2 is a pretty popular weight loss supplement (squeaking into 19th position on BodyBuilding.com's Top 50 list of fat burners at the time of this writing), and therefore, worth a good long look. According to the advertising I saw, Amp contains...

"... ingredients that are turning the dietary fat loss market on its head."

Does it?

And what about the claim that taking this product and its unique blend of ingredients...

"...results in tremendous energy boost and appetite suppression."

Well, let's find out by having a closer look at Amp 2 and its ingredient profile. A single 2-capsule serving contains 483 mg of the following ingredients...

Caffeine Anhydrous: No surprise here; caffeine's got a well established record as a thermogenic, and does help with weight loss (see Am J Clin Nutr. 1989 Jan;49(1):44-50, Am J Clin Nutr. 1980 May;33(5):989-97). It also cheaply and effectively addresses the most common complaint of dieters; lack of energy. Zingerone: A component of ginger, small animal studies performed on zingerone have been positive for weight loss (Yakugaku Zasshi. 2008 Aug;128(8):1195-201) albeit the dosage used (170 mg/kg) is too high to be transferred into humans (a 180 lbs. person would need to take about 14 grams a day). Raspberry Ketone: a phenolic compound derived from red raspberries, raspberry ketones have only really been shown effective in animal studies (you can view the details of the study here). You are not a mouse, and the results of animal studies do not necessarily translate over to humans.

An unpublished pilot study performed on Razberri-K (a patented form of raspberry ketones) demonstrated it enhanced post-exercise fat oxidation, although the results were apparently not large enough to be statistically significant.

Fursultiamine: A derivative of Vitamin B1, the Amp 2 advertising states that this ingredient may

"...improve exercise performance and reduce muscle fatigue."

I did find some evidence that high-dose thiamine supplementation (100 mg/day) does appear to reduce exercise reduced fatigue (Metab Brain Dis. 1996 Mar;11(1):95-106).

On the other hand, studies performed with large doses of Fursultiamine (1,000 mg/day) showed it to have no effect on exercise performance (see Eur J Appl Physiol Occup Physiol. 1997;75(6):520-4).

Dimethylpentylamine or DMAA (Constituent Of Geranium Oil): DMAA is an adrenergic amine that acts as a CNS stimulant. It was originally patented by Eli Lilly as a nasal decongestant in 1944, but largely abandoned until re-introduced as a supplement ingredient (Geranamine™) by Proviant Technologies (the parent company of Ergopharm). Although there's no current research on it, DMAA's gotten mostly rave reviews from users for its effects on mood, focus and energy.

When the original AMP came out, it created a bit of a hubbub due to its DMAA content, even receiving some pretty negative publicity in the Washington Post.

Green Coffee Bean Extract: This ingredient is likely standardized for something called "chlorogenic acid." Although there is some animal data that indicates this compound has weight loss benefits (see BMC Complementary and Alternative Medicine 2006, 6:9), there is currently no human-based clinical data available. Evodiamine: a Chinese fruit that some claim burns fat by increasing the body's production of heat, as well as reducing the body's ability to store fat. Although a preliminary animal study shows promising results, to date there's no evidence showing evodiamine works in people. Kaempferol: This ingredient, usually derived from grape seed, has shown anti-obesity activity in animal and in-vitro experiments, but human data is lacking. Coleus forskohlii extract (On BodyBuilding.com, the ingredients list includes forskohlii, but the product label does not): Usually standardized for forskolin, clinical data indicates that this ingredient provides modest benefits for fat loss.

As you can now see, Amp 2 doesn't exactly contain ingredients that are "turning the fat loss market on its head."

With the exception of caffeine, the fat burning value of the remainder of the ingredients is largely speculative, based almost entirely on animal-derived clinical data.

That's not to say some of these ingredients might be proven helpful in humans in later studies, it's just at this time, those studies don't exist.

So as I say... their value is largely speculative.

Next, there's the issue of dosage. ErgoLean's AMP 2 contains 160 mg of caffeine per serving, which means there's only 323 mg of ingredients left— to be divided between the remaining 8 ingredients. That's not a lot, obviously, and pretty much guarantees that most ingredients are going to be present only as "label dressing" (i.e., they make the label look impressive, but are unlikely to be present in a dosage high enough to elicit any effect).

As an example, consider the coleus forskohlii included in this product. One study (Obesity Research (2005) 13, 1335–1343), demonstrated modest weight loss with this ingredient... when 250 mg of 10% forskolin extract was taken twice a day. In this formula, we don't know how potent the extract is, but we do know there's nowhere near the required 500 mg here.

At the same time, reviews of this product are largely positive, most praising Amp 2's clean and "jitter-free" boost of energy, which could very well be attributed to its dimethylpentylamine content (DMAA does not need to be present in a huge dose in order to be effective. In fact, the DMAA / caffeine combo pretty much guarantees you're going to "feel" this product, and low dosages or not, it might be smart to start off with a half-dose to assess your tolerance.)

Little is said about its fat burning characteristics, on the other hand.

The product label recommends anywhere from 1-4 caps per serving—and at 4 caps, this product becomes pretty potent (320 mg of caffeine alone), but expensive; a 120 capsule bottle retails for around $35 at BodyBuilding.com. You'll go through that pretty quickly taking a 4-capsule dose a couple of times a day.

Have you used ErgoLean Amp 2? Share your
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5) To watch our video on deceptive billing practices, click here!
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7) For an introduction to fat burners; what they are, what they do, and what you absolutely need to know about them, click here!

To find a specific product review, use the search function on the top right hand side of this page, or the alphabetical listing to the right of this table.

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German American Technologies' Jet Fuel Pyro Review:

German American Technologies' Jet Fuel fat burner has been a popular weight loss supplement for some years now, and the newer Pyro version claims to be...

"...an advanced 4-part professional formula carefully engineered to be used by athletes, those competing, hardcore bodybuilders, and physique models who need to diet down, burn stubborn adipose fat faster and easier."

Of course, when it comes to fat burners, talk is cheap. When the rubber hits the road, how does Jet Fuel Pyro measure up? To answer that, we need to take a close look at the ingredients profile.

What's in it?...

1) The Jetfuel® Rapid Fat-Melting, Ultra Clean/Clear, Xtreme Energy Blend: A 1657mg blend of the following 16 ingredients...

Sesame Seed Oil: The original Jet Fuel contained an oil-based delivery system, designed to deliver a smoother and longer lasting thermogenic effect. The advertising for the "pyro" version makes no note of this, so I'm assuming the oil content of this product is included for its thermogenic properties alone.

Sesame seed oil contains a lignan called "sesamin." It's occasionally included in weight loss supplements on the premise that the active compound (sesamin) increases the oxidation of fatty acids in the liver and muscle tissue (which should result in increased fat burning), as well as reducing the levels of enzymes which contribute to the storage of fat. There's no credible human-based evidence to validate this claim—big surprise, right?

German Miglyol Oil: Here's a classic supplement retailer trick; using a less familiar and more "technical-sounding" name for a well-known ingredient. In this case, it's MCT oil (medium chain triglycerides, usually derived from coconut oil). MCT oil played a big part in the delivery system of the original Jet Fuel, and it's back again here, although its presence is disguised.

There is some evidence MCT oil may be helpful for weight loss, although at vastly larger dosages than included here.

CLA (Conjugated Linoleic Acid): A non essential fatty acid, which, when present in a potent enough dose (around 3 grams/day) has been shown to be moderately helpful for weight loss. Unfortunately, with only 1657 mg of ingredients in this 16-ingredient blend, we can be sure CLA provides little more than "label dressing" here. Caffeine Anhydrous: A well-known thermogenic with established, albeit relatively mild, weight loss benefits (see Am J Clin Nutr. 1989 Jan;49(1):44-50, Am J Clin Nutr. 1980 May;33(5):989-97).

It's also used to cheaply and effectively address the most common complaint of dieters—fatigue.

Panex Ginseng: A common adaptogen, with immune-boosting characteristics. Green Coffee Bean Extract: Hard to know what role this ingredient plays here, since we're not told what it is standardized for—it is probably something called "chlorogenic acid." Although there is some animal data that indicates this compound has weight loss benefits (see BMC Complementary and Alternative Medicine 2006, 6:9), there is currently no human-based clinical data available. Guarana Extract: This Brazilian shrub is often included in weight loss products as an additional source of caffeine, although it has both antioxidant and diuretic properties as well. Fucoxanthin: A carotenoid isolated from brown seaweed, and used in diet pills for its supposed fat blasting characteristics. This, based on the strength of positive animal studies. Newer studies show the combination of fucoxanthin and pomegranate seed oil to be beneficial for weight loss. Human data on fucoxanthin is highly lacking, however. Grapefruit Extract: Because of the ambiguous nature of the way this ingredient is labeled, it's difficult to assess its role here. Is it standardized for narinigin? After all, naringin is often included in products to enhance the bioavailability of ingested nutrients/nutraceuticals, although specific benefits have not been demonstrated.

It also has cholesterol-lowering effects, and can affect drug metabolism. Grapefruit seed extract, on the other hand, has anti-microbial properties; nothing wrong with that, of course, but not a valid reason for its inclusion in this product.

Vinpocetine: Often added to fat burners and pre-workout, stimulant blends designed to improve focus, concentration and training drive (see BSN's No-XPLODE as an example). Yohimbine HCl: The standardized extract of the bark of the African Yohimbe tree is yohimbine. This compound is often used as a natural aphrodisiac. It is also sold as a drug (in the U.S., a popular brand is Yohimex containing 5.4 milligram of yohimbine hydrochloride per tablet) and is used to treat impotency, dilate the pupil of the eye, and stimulate fat loss (studies indicating weight loss are promising but not revolutionary -- see Isr J Med Sci. 1991 Oct;27(10):550-6). Orange Peel Powder: It's not revealed what this ingredient is standardized for; it's likely for synephrine (see below). Ginger Root Extract: Some small animal studies performed on zingerone (a component of ginger) have been positive for weight loss (Yakugaku Zasshi. 2008 Aug;128(8):1195-201) albeit the dosage used (170 mg/kg) is too high to be transferred into humans (a 180 lbs. person would need to take about 14 grams a day).

Ginger also seems to accelerate gastric emptying... the opposite of the sort of thing dieters want (Eur J Gastroenterol Hepatol. 2008 May;20(5):436-40).

cAMP (3'-5'-Cyclic Adenosine Monophosphate): cAMP is a "cellular regulator." In other words, this compound is required to "spark" many intercellular processes. An increased concentration of cAMP can have such "total-body" effects as raised thyroid hormone levels and increased fat burning.

Most studies performed on the effectiveness of cAMP for weight loss have been performed on herbal ingredients (i.e. forskohlin, clary sage) thought to stimulate it. This study (using 250 mg twice daily doses of 10% standardized forskolin) showed a modest weight loss effect.

Raspberry Ketones: Becoming more popular in fat burners, as retailers claim it has anti-obesity effects. Unfortunately, most positive clinical study data has been derived from animal studies, and human studies haven't exactly been overwhelming. Synephrine HCl: Once thought to be a credible alternative to ephedra, clinical evidence has not been kind to synephrine. The most positive study I could find concluded...

"CA (citrus aurantrium) alone increased thermogenesis, on average, by 4% (52), a response that is statistically significant but not necessarily clinically significant, representing an average 1 kg over 6 months."

For more, see the full synephrine review.

Before I continue on with the remaining Jet Fuel Pyro ingredients, a couple of words about this element of the formula.

It is impressive looking, I agree.

However, most of these ingredients are present at a dosage far too low to have any real effect.

Consider, for example, the ingredient yohimbine. Because of its potent CNS stimulating properties, it is rarely found in any supplement in a dose greater than 3-8 mg.

Since ingredients on the label are required to be listed in the order of prominence (i.e., the ingredients present in the highest dose are listed first, following along in decreasing order), we can therefore assume every ingredient listed after yohimbine (ginger root, orange peel extract, cAMP, raspberry ketones, synephrine) is present in a dose less than 3-8 mg. That means they add absolutely nothing of value to this formula, and serve only as label dressing.

2) The Jetfuel® Super Uplifting, Serotonin/Dopamine/Anti-Fatigue Blend: A 377 mg blend of the following ingredients...

3) Jetfuel Ultra High-ORAC Antioxidant, Cellular Recovery/Repair Blend: A 135 mg blend of Indian Goosberry, Acai Berry, Mangosteen Extract, Grapeseen Extract, Maca Extract. At such a tiny dosage, it's a wonder why German American Technologies even bothered with these ingredients... unless it is to capitalize on the popularity of current "superfruits" and to make the label look impressive. Forget it, I just answered my own question...

4) JetFuel® Bio-Nutrient, Maximum Absorption Blend: Contains 4.5 mg of BioPerine®, a proprietary black pepper extract which has been shown to improve the bioavailablility of certain ingredients. It's a common enough supplements in many supplements for this reason.

So there you have it. Jet Fuel Pyro. In a nutshell.

As you noticed, it contains a ton of impressive looking (and sounding) ingredients. But as is the case with ALL capsule/tablet based supplements, there is only so much stuff you can cram into a manageable dose. And, when you consider that like prescription drugs, the medicinal plants, food compounds and herbs that are typically found in weight loss products need to be present in a potent enough dosage to have any effect, you can only come to one conclusion...

Most of the ingredients in Jet Fuel Pyro are hideously under dosed.

That doesn't mean Jet Fuel Pyro is useless, of course. I suspect this product contains plenty of caffeine—and when combined with the yohimbine, synephrine and Chocamine also included in this formula—it is likely to give one heck of a boost of energy (the aforementioned ingredients all do offer mild thermogenic effects, even if what they deliver is not consistent with the advertising claims).

In fact, the advertising copy I reviewed talked almost as much about Jet Fuel Pyro's ability to increase "training intensity" as it did about its weight loss characteristics. I have no doubt it will accomplish this.

And quite frankly, most people I have received feedback from (they used the original formula) seemed to be quite happy with their experiences. I would imagine the same thing would apply the this newer formulation.

But as a weight loss miracle, it falls WAAAYYY short.

Have you used Jet Fuel Pyro? Share your
comments and read Jet Fuel Pyro user reviews / testimonials, click here!

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3) To see which products we recommend, click here!
4) To read what our visitors say about us, click here!
5) To watch our video on deceptive billing practices, click here!
6) To read the review of our recommended diet program, click here!
7) For an introduction to fat burners; what they are, what they do, and what you absolutely need to know about them, click here!

To find a specific product review, use the search function on the top right hand side of this page.

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US visitors should submit a complaint to the US Federal Trade Commission!

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