Review: Revolution's Thermogenic Push for Women

Revolution's Thermogenic Push is a "extreme fat burner" for women, and is advertised to...

Boost the metabolismIncrease energySuppress appetiteProvide mood supportReduce water retention

This, of course, is the standard series of claims made for just about any weight loss product targeting women. But there are problems with making too many promises; given the logistics of capsule size and the required minimum effective dose of the appropriate ingredients, most of the time it's next to impossible to deliver on all of them.

And, by creating a product that promises to be "all things", the retailers dilute the overall effectiveness of the product because they can't focus on a single element of the formula.

So let's take a closer look at Thermogenic Push for Women and see if that's the case.

One capsule contains 408 mg of ingredients—and there are 11 of those in total. Recommended dosage is 2 caps in the morning, and 1 cap later in the afternoon. Given the large number of ingredients and relatively small serving size, it's not unreasonable to assume most ingredients will not be present in a dosage strong enough to elicit any effect.

For some ingredients, this will be fairly obvious, but not so for others—since Revolution does not provide a detailed breakdown of the ingredient profile. In other words, we don't know which ingredients are included at what dosages.

Anyway, let's take a closer look at them...

Dandelion root: This ingredient is included as a diuretic—therefore addressing the "water retention" claim. And yes, there is some preliminary evidence it works in this regard. However, products that are focused on water loss contain either a significant amount of dandelion root (250-500 mg and up), or combine it with other natural diuretics. At the two capsule dosage, Thermogenic Push may contain enough dandelion root to elicit an effect, although we cannot verify that for sure. Green tea extract: Green tea exhibits numerous characteristics that make it a helpful supplement for weight loss, although its effects are extremely exaggerated. Like all supplements, it needs to be standardized for the appropriate compounds and be present in a potent enough dosage to offer any effect. The retailers of Thermogenic Push don't reveal what they've standardizing their tea for, and how much ingredient is included. It's value, therefore, is somewhat debatable. Caffeine: The obvious energy booster in this formula; caffeine has a well established record as a mild thermogenic, and does deliver mild weight loss results (see Am J Clin Nutr. 1989 Jan;49(1):44-50, Am J Clin Nutr. 1980 May;33(5):989-97). It also cheaply and effectively addresses the most common complaint of dieters; lack of energy.White willow: A natural source of salicin, an anti-inflammatory similar to aspirin. In the old days, white willow was used as an alternative to aspirin in the ephedra / caffeine / aspirin stack. In non-ephedra based fat burners like this one, white willow offers no demonstrated benefit beyond that as an anti-inflammatory. Hoodia: An African succulent advertised to suppress appetite and enhance weight loss. I say "advertised" because there is no clinical evidence to validate these claims. Plus, there are additional problems with hoodia which may call its effectiveness into question. Yohimbe: From our glossary...

"The bark of Pausinystalia yohimbe, a tree indigenous to Western Africa. The active ingredient in yohimbe is the alkaloid yohimbine. Yohimbe bark extracts are often added to fat loss supplements and/or “male” enhancement supplements, although the amount of yohimbine is variable, and often low."

Yohimbe also possesses stimulant qualities, which may enhance the "energy-boosting" effect of the caffeine in this product. There have been studies performed on its weight loss characteristics, for which of course, it is used in this formula. Study results have been less than stellar: they range from showing no effect at all (J Pharmacol. 1986 Jul-Sep;17(3):343-7) to a slight improvement. This study concluded...

"The results obtained warrant further research on the applicability of alpha 2-receptor inhibitory drugs as a supplementary management in the treatment of obesity."

Evidence does validate yohimbe's "lipid-mobilizing action", however.

N-acetyl-l-tyrosine: In large doses (100-150 mg/kg of bodyweight) tyrosine helps with cognitive stress and fatigue (see here and here!). It's often added to weight loss supplements on the basis that as a precursor to the thyroid hormone thyroxine, it may elevate thyroid levels, and consequently, the metabolism. There is little evidence this is the case however. Evodiamine: Several thermogenic products I've investigated recently include Evodiamine, a compound derived from the Chinese fruit Evodia Rutaecarpa.

It's claimed to burn fat by increasing the body's production of heat, as well as reducing the body's ability to store fat.

Although a preliminary animal study shows promising results, to date there's no evidence showing evodiamine works in people.

Cayenne powder: At extremely large doses (3-10 grams) evidence suggests cayenne can elevate the metabolism, reduce appetite and decrease fat intake (see study abstracts here, here and here as examples). At the dosage included here, we doubt it will do anything much. Vinpocentine: An alkaloid derived from periwinkle that affects cerebral blood flow, memory and learning. Vinpocentine is often added to pre-workout, stimulant blends designed to improve focus, concentration and training drive. It does not need to be present in a large dosage in order to work, however; most effective products only contain 10 mg of ingredient. 5-HTP: Also known as 5-hydroxytryptamine and derived from Griffonia simplicifolia, it is used as an alternative treatment for depression, and, at a much larger dosage (900 mg/day) as an aid for weight loss and appetite suppression.

And there you have it; the entire Thermogenic Push formula deconstructed.

How's it measure up?

At the risk of sounding like a broken record, this is a difficult formula to analyze effectively since a complete breakdown of each ingredient's potency is not revealed. Ingredients like vinpocentine, 5-HTP, caffeine, dandelion root and green tea may be present in dosages high enough to provide some benefit, but it's impossible to tell.

Other ingredients are much less likely to be included at the dosage shown helpful in various clinical studies (if the ingredients are listed in decreasing order of amount, as they are supposed to be).

Since Revolution is charging a premium price for their product—$40 for a month's supply at BodyBuilding.com—we feel they need to come to the table with some specifics—anything to justify the cost they are charging.

For a vastly reduced cost you can buy each of the three ingredients most likely to be present in a useful dosage, and stack them together...

... and probably get 90% of the benefits for a third of the cost. Despite the slick packaging and cool name, there's not a lot here to justify the elevated cost.

Have you used Thermogenic Push for Women? Share your comments
and read user reviews / feedback and testimonials on Thermogenic Push, click here!

UltimateFatBurner.com is proud to offer you hundreds of science-based supplement reviews. If you know the name of the product you want to investigate, or you want to browse a list of all the supplements reviewed on this site (includes vitamins, body building supplements, functional foods, fat burners etc), this is the option for you. Click the "Search Supplement Reviews" link directly to the right to be taken to a new page where you can search and/or browse listings. Alternatively, you can use the search box at the top right of this page. If don't you know the name of the product you are looking for, but are instead looking for a product recommendation based on certain preferences or symptoms, slide your mouse over the text to the right and drill down until you find the option that best suits your needs. Click on that option to continue.UltimateFatBurner.com has a growing inventory of informative videos. If you prefer getting your information in video format, this option is for you. Not sure where to begin? Why not start by investigating some of our most popular pages? Because the nutritional supplement industry is very loosely regulated, it is a fertile breeding ground for fraudulent behavior. UltimateFatBurner.com features three "Walls of Shame"; the first highlights companies that have poor ratings with the Better Business Bureau and established track records of poor customer service and deceptive billing tactics. The second highlights a list of companies that have used the threat of lawsuits to attempt to get us to remove or alter our reviews. The third lists companies have violated copyright laws by stealing our content and passing it off as their own. Have you been ripped off by a supplement company? Were you treated poorly, ignored, refused a refund, overbilled or billed on a regular monthly basis without your consent? You're in the right place. Just move your mouse to the right, and in one swift quick click, we'll show you how to complain to the appropriate authorities, as well as provide you with some crucial "need to know" information to prevent anything like this ever happening again. A successful weight loss protocol includes a smart diet and exercise program. We've reviewed many, but this selection contains a few of the better ones worth investigating.

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Review: Hydroxycut Shape For Women

Hydroxycut Shape is the "professional strength weight loss formula" for women. According to the advertising I viewed...

"Fast weight loss is important to professionals who make their living looking good in front of the camera, on the stage or on the set – being in shape is their livelihood. That’s why there is Professional Strength Hydroxycut Shape – the professional solution for weight loss with key ingredients clinically proven in 8- and 12- week studies. Use as part of your healthy, active lifestyle including your nutrition and exercise program."

After reading this, I imagine you're wondering...

Are Vegas showgirls, Broadway actors and dancers and Hollywood starlets using "Shape" to stay in shape? And have the key ingredients actually been "clinically proven" as the good folks at Iovate / Muscle Tech insist they have?

To answer these questions, let's take a look at the ingredient profile, and especially the "W8 Lean™ Complex", a blend of four ingredients advertised as being proven in two clinical trials.

Incidentally, this exact same foursome of ingredients is labeled as the "HydroxyPro" complex in the Hydroxycut Hardcore Pro series fat burner.

In addition to a peppering of calcium, Vitamin C, folic acid and iron, two capsules contain an under-whelming 383 mg of ingredients, divided up between the following...

 L-Carnitine Tartrate: Carnitine has been a common ingredient in weight loss supplements almost since the time when dinosaurs roamed the earth.

And that's despite the fact that clinical evidence validating its effects is contradictory, even when consumed in multi-gram doses. Quite simply, the carnitine in this formula is present only as label dressing—it's present at a dose much too low to offer any effect.

Caffeine: Caffeine is a well known thermogenic with a proven track record of modest weight loss (see Am J Clin Nutr. 1989 Jan;49(1):44-50, Am J Clin Nutr. 1980 May;33(5):989-97).

Almost every stimulant-based fat burner on the planet contains it for this, and a couple of other good reasons—its cheap, and it effectively addresses the fatigue so many people feel contributes to their inability to execute and maintain an exercise program.

According to the product labeling, this product contains 200 mg of caffeine per serving, which means you'll be consuming a whopping 600 mg per day when you're up to the full 6 caps per day.

That means that this is not a product for those of you who are sensitive to stimulants, or who have an underlying health issue like heart disease, high blood pressure and so on. It also means you'll definitely "feel" this product—the caffeine in this product will definitely provide you with a "boost" of energy, if that's what you want.

W8 Lean™ Complex: Ah, here's that blend of 4 ingredients responsible for the "amazing" weight loss effects of this product. They are Alchemilla vulgaris extract, Olea europaea extract, Cuminum cyminum extract, and Mentha longifolia extract.

And are they "clinically proven" as claimed?

Sort of. While the folks at Muscle Tech / Iovate aren't revealing the study they are referencing for us to verify, there has been a study published on this quartet of ingredients that we can check out.

According to the advertising, participants lost an average of 20.94 over a 12 week period; not particularly impressive when you consider that equates to 1.75 lbs. of weight loss per week (well within the realms of what you can accomplish on your own with proper diet and exercise), and participants were restricted to a calorie reduced diet.

The devil, however, is in the details.

In this case, the details make it difficult to allot a ton of credence to the study results. For example...

1) The participants in the study did not have their caloric intake restricted or monitored. Instead, they were asked only to restrict their meals to three per day. Since the calorie value of meals can vary dramatically depending on your food choices, this essentially places each individual into his/her own unique study group—as no two participants will consume exactly the same amount of calories.

Think about it: if you know participants are still over-consuming calories in a significant amount, yet losing weight, that makes these ingredients significantly more valuable. If participants are under-consuming calories, that undermines the study results, does it not? Fact is, if you don't know how many calories your audience is consuming, it's impossible to accurately attribute any success or failure to a series of ingredients.

2) This study was not placebo controlled. In other words, the folks in the study group taking the product knew that they were, while the folks in the control group received nothing.

This is a big deal.

Folks taking the product may have seen it as a license to eat more (or perhaps less). The folks in the control group had very little incentive to stick to the straight and narrow.

As we both know, the placebo effect is very real, which is why any good study puts both the study group and the control group on a pill, with neither of them knowing who is getting the real thing.

I can't see any reason why this wasn't done in this case... unless you want to tip the scales towards a favorable outcome, that is.

In other words, all this study does is indicate the need for a properly controlled and monitored one to further confirm or dispel the claims that this quartet of ingredients actually "works". Perhaps the studies referenced by Muscle Tech used better methodology (if they exist at all), but since we can't examine it, we'll never know, right?

Gamma-oryzanol: A group of constituents derived from rice oil bran. Normally, it is included in supplements to lower cholesterol or raise testosterone and / or hGH (human growth hormone) levels. Clinical evidence supporting its use however, is extremely scarce.    L-ornithine HCl: An amino acid, also used to boost hGH levels and athletic performance. However, clinical data does not bear out ornithine's hGH-boosting effects (see Int J Sport Nutr. 1993 Sep;3(3):290-7). 

And that, my friends, is the Hydroxycut Shape for Women formula in all its "glory".

The core of this product is the combination of its caffeine content and the quartet of "clinically proven" ingredients, which as you now know, are clinically proven by a study that has some serious issues with its methodologies.

And, even if these results stood up to real scrutiny, it's not like the results were revolutionary; 1.75 lbs. a week is on par with what you can accomplish with proper diet and exercise.

Well, if you've enjoyed previous Muscle Tech / Iovate offerings (like Hydroxycut Max, for instance) you'll probably enjoy this product simply for its caffeine content. But caffeine is cheap (you can buy an entire bottle of 200 mg tabs for around $5) and that on its own hardly justifies the cost of a purchase.

And in our opinion, Muscle Tech hasn't proven the "quartet" of special ingredients provides any more than the mildest weight loss benefits (if any at all), and therefore we'd argue they don't deserve your money. Of course, we can't prove a negative, and it's possible we're wrong... but we highly doubt it.

And if you happen to be a Vegas showgirl, Broadway actor or dancer or a Hollywood starlet... sorry, there`s no magic pill here.

Why don't you tell us what you think? Have you used the new Muscle Tech Shape offering? What did you think...

Have you used the Hydroxycut Shape for Women?
Share your experience, and / or read user reviews, comments, and testimonials
on this product, click here!

UltimateFatBurner.com is proud to offer you hundreds of science-based supplement reviews. If you know the name of the product you want to investigate, or you want to browse a list of all the supplements reviewed on this site (includes vitamins, body building supplements, functional foods, fat burners etc), this is the option for you. Click the "Search Supplement Reviews" link directly to the right to be taken to a new page where you can search and/or browse listings. Alternatively, you can use the search box at the top right of this page. If don't you know the name of the product you are looking for, but are instead looking for a product recommendation based on certain preferences or symptoms, slide your mouse over the text to the right and drill down until you find the option that best suits your needs. Click on that option to continue.UltimateFatBurner.com has a growing inventory of informative videos. If you prefer getting your information in video format, this option is for you. Not sure where to begin? Why not start by investigating some of our most popular pages? Because the nutritional supplement industry is very loosely regulated, it is a fertile breeding ground for fraudulent behavior. UltimateFatBurner.com features three "Walls of Shame"; the first highlights companies that have poor ratings with the Better Business Bureau and established track records of poor customer service and deceptive billing tactics. The second highlights a list of companies that have used the threat of lawsuits to attempt to get us to remove or alter our reviews. The third lists companies have violated copyright laws by stealing our content and passing it off as their own. Have you been ripped off by a supplement company? Were you treated poorly, ignored, refused a refund, overbilled or billed on a regular monthly basis without your consent? You're in the right place. Just move your mouse to the right, and in one swift quick click, we'll show you how to complain to the appropriate authorities, as well as provide you with some crucial "need to know" information to prevent anything like this ever happening again. A successful weight loss protocol includes a smart diet and exercise program. We've reviewed many, but this selection contains a few of the better ones worth investigating.

Legend: Place your mouse pointer over each icon for an explanation of each accompanying heading. Place your mouse pointer over each title heading to "drop down" additional options. Click on the one that interests you (not all titles have additional options; in this case click the heading in question).

Since 1999, our visitors have been trusting our science-based reviews (why should you care about science?) to provide them with the real skinny on weight loss, dieting, and sport nutrition supplements. Unlike our competitors, our mandate is not the sale of supplements (we are fans of good products though, and will make a recommendation should the circumstances merit), it's the education of our visitor... you!

UltimateFatBurner.com is supported by advertising, not by product sales. This allows us to present a real, unbiased synopsis of each product we review. And check our real visitor comments too. These aren't the manufactured testimonials that you'll see elsewhere on the Net. They are real comments from real, often angry people -- visitors who have used these products, and often, aren't too darn happy about it.

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365 Day Fat Burner Review: A Fat Burner For Every Day Of The Year?

A fat burner for every day of the year? Yep... at least that's the idea behind the 365 day fat burner. Here's the concept: you get a whole big bunch of amazing fat burning ingredients at an unheard of price, and you don't need to buy anything again for an entire year (or every 6 months, if you double the one-per-day dosage—which is the recommendation of the retailer!).

The retail web site discusses how much you'll save by choosing the 365 day fat burner over typical "expensive" weight loss products you would normally buy from month to month. Then, as if to demonstrate this amazing value, they display the impressive list of ingredients included in the 365 day fat burner.

What they do not do, of course, is show you exactly how much of each ingredient you're getting.

And herein lies the problem. Take one ingredient, glucomannan, for instance. Studies have shown that 1 gram of glucommann, taken prior to meals, can help with weight loss (see full review for accompanying clinical references).

How much does the 365 day fat burner contain? No one knows for sure.

But we can be darned certain it contains nowhere near the amount shown to be helpful in studies.

How can we be sure of that?

Pure logistics.

A gram (1,000 mg) of glucomannan may not sound like much, but you'd need to take two large capsules of the stuff to obtain that dosage.

An effective daily dosage would require 6 large capsules. You'd need slightly more than 2,100 large capsules to supply a years dose of an effective dose of glucomannan alone.

And the 365-day fat burner contains 13 ingredients in 365 capsules! If a few of the more promising ingredients were present in doses strong enough to do anything, these capsules would be way, way, WAY too large for you to ever be able to swallow them.

Additionally, there's the simple issue of cost: including an effective dose of several of the ingredients (green and oolong teas, guggul, etc) would be expensive— so expensive that we can rule out their inclusion in all but the tiniest amounts.

I would be surprised if the 365-day fat burner contained anything but caffeine in a useful dose. Caffeine, after all, is an ingredient consumers can "feel", and it's cheap, cheap, cheap.

To make matters worse, there is absolutely no company information provided on the product web site. Who is selling this stuff? How can you obtain remuneration for a product you are not happy with? Who can you complain to in case of an incorrect billing issue?

Frankly, there's only one reason for any company to isolate themselves from you, the customer. And that's to prevent you from obtaining recourse for any unsatisfactory issue. Stand up companies are happy to identify themselves. Those who do not... well, I'll let you make your own judgment call on that one.

The bottom line is simple; without knowing what dosage the various ingredients are included in, it's impossible to determine what sort of value this product actually offers. But logistics and simple issues of cost indicate it's probably not much.

Quality products with potent formulations cost money, there's no way around it.

In the end, you get what you pay for!

Have you used the 365 Day Fat Burner? Share your comments
and read 365 Fat Burner user reviews / testimonials, click here!

UltimateFatBurner.com Recommended Quick Links:

1) For a listing of popular women's fat burner reviews, click here!
2) For a listing of popular "unisex" fat burner reviews, click here!
3) To see which products we recommend, click here!
4) To read what our visitors say about us, click here!
5) To watch our video on deceptive billing practices, click here!
6) To read the review of our recommended diet program, click here!
7) For an introduction to fat burners; what they are, what they do, and what you absolutely need to know about them, click here!

To find a specific product review, use the search function on the top right hand side of this page.

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Neogenix Velocity XT Review: Pre-Workout Energy Rush

The Velocity XT® sales copy focuses on the product's energy-elevating characteristics, with a secondary nod to its fat burning capabilities...

"Whether you are looking for an all-day energy boost, to incinerate body fat, or just a pre-workout energy rush; Velocity XT® is the only choice!"

With Velocity XT, Neogenix has bucked the trend of jamming 3-dozen under-dosed ingredients into their formula (a big thumbs up for that!) and instead, has opted for something much simpler. A single 3-capsule, 1260 mg serving contains a mere 5 ingredients!

Very refreshing!

Of course, because it's a proprietary blend, we can't be 100% certain of the exact amounts of any of the ingredients. Nonetheless, with so few included, it's at least possible they are all included at a worthwhile dosage.

So what's in Velocity XT?...

1) Thiamine Disulfide Butyrate: Thiamine, also known as Vitamin B1, plays an important role in energy metabolism, and is thought to play a role in appetite suppression. This novel, potent version of thiamine is being touted as a potent enhancer of physical and mental energy—especially when combined with caffeine (as it is in this formula).

2) Caffeine: On its own, caffeine is a mild thermogenic with demonstrated benefits for weight loss (see Am J Clin Nutr. 1989 Jan;49(1):44-50, Am J Clin Nutr. 1980 May;33(5):989-97), although some data indicates it offers greater benefits to lean individuals that those who are overweight (see Am J Physiol. 1995 Oct;269(4 Pt 1):E671-8).

Of course, caffeine is cheap, and works effectively to provide a "boost" of energy many people find helpful, especially at the end of the day when a little "extra" is needed to make it to the gym for a productive workout.

3) Phenylethylamine (PEA): PEA is an "amphetamine-related", mood-elevating chemical naturally present in foods like chocolate and was once thought to be the reason people were "chocoholics." It is generally used in fat burner supplements in the hopes it will elevate mood and promote a feeling of well being (some retailers claim it works as a thermogenic, but there's no evidence to support this assertion).

Perhaps not surprisingly, there is a problem with PEA though.

It is too rapidly metabolized by the enzyme monamine oxidase (MAO) to be of much use to us.

That's why most products focused on squeezing the most from PEA also contain natural monamine oxidase inhibitors (MAOI's).

Does this one? With that said, let's look at the next ingredient in this formula...

4) Hordenine: A biogenic amine found in a number of plants, including barley and several species of cacti. It’s alleged to be beneficial for fat/weight loss, due to its ability to stimulate the release of norepinephrine, although there is no research to confirm this claim.

This ingredient is also included in many formulations that contain the aforementioned phenylethylamine for the reason that it may increase its effectiveness. According to the most credible research I've seen, hordenine isn't a MAOI per se, but a highly selective substrate for MAO-B.

What does this mean in plain English?

It means that the enzyme responsible for the breakdown of phenylethylamine is really, really attracted to hordenine, meaning that if the two compounds are both present at the same time, it will prefer to act upon hordenine, allowing the PEA to slip into the bloodstream intact. That's the theory anyway. How well it works in the real world is a matter of some speculation.

5) 1,3-Dimethylamylamine: This compound is also known as "methylhexaneamine." 1,3-Dimethylamylamine (DMAA), is an adrenergic amine that acts as a CNS stimulant. It was originally patented by Eli Lilly as a nasal decongestant in 1944, but largely abandoned until re-introduced as a dietary supplement (Geranamine™) by Proviant Technologies, the parent company of Ergopharm.

Although there's no current research to validate the claims being made by the retailers (for performance, weight loss, or otherwise), it's not unreasonable to assume that as a potent CNS stimulant, it does offer some thermogenic effects. As previously indicated however, how much so has yet to be established by any credible studies.

DMAA has gotten mostly rave reviews from users for its effects on mood, focus and energy. A few have reported problems with higher doses, however, so some caution is advised when supplementing.

This is not the first weight loss product to contain DMMA. Ergolean's AMP (and now AMP 2) contains it, and garnered a fair bit of mainstream negative publicity, with one expert calling the legality of DMAA into question and saying...

"The chemical structure is similar to amphetamines and ephedrine..."

Other newer DMAA-containing products include Ripped Freak and USP Labs' Oxyelite Pro.

Although I haven't used any DMAA-containing thermogenics, I have experimented with a DMAA-based pre-workout supplement (Nutrex's HemoRage) and I can testify to the potency of DMAA for getting you "jacked."

So there you have it; Velocity XT in a nutshell.

How's it measure up?

Well, on the "energy" front, I have no doubt it works very well indeed—the caffeine / DMAA / thiamine disulfide stack pretty much ensures that.

The PEA/hordenine blend is the dark horse here—it's difficult to say how much it contributes to the formulation. If the hordenine does inhibit the metabolism of PEA, that may take Velocity XT into the "tear your head of territory" of other DMAA supplements like the aforementioned Ripped Freak or OxyElite Pro.

As far as true "fat loss" ingredients go, only caffeine has any credible data behind it. This product is definitely strong on the "energy" ingredients and short on the proven "fat burning" ones.

One thing I'm happy about is that a full dose is served up in a 3-capsule serving, which means you can easily start with a small, single-capsule dose to assess your tolerance... something I highly recommend in the case of this, and any other DMAA containing supplements.

So, should you experiment with Velocity XT?

Well, if customer feedback on BodyBuilding.com is any indication (and visitor feedback must always be taken with a grain of salt, even on this site) this product OVER-delivers on the energy front. If that's what you're looking for, and don't have any underlying health issues like high blood pressure or heart issues, this product is probably as good as any.

Just don't expect any fat burning miracles from it.

Have you used Velocity XT? Share your
comments and read Velocity XT user reviews / testimonials, click here!

UltimateFatBurner.com Recommended Quick Links:

1) For a listing of popular women's fat burner reviews, click here!
2) For a listing of popular "unisex" fat burner reviews, click here!
3) To see which products we recommend, click here!
4) To read what our visitors say about us, click here!
5) To watch our video on deceptive billing practices, click here!
6) To read the review of our recommended diet program, click here!
7) For an introduction to fat burners; what they are, what they do, and what you absolutely need to know about them, click here!

To find a specific product review, use the search function on the top right hand side of this page, or the alphabetical listing to the right of this table.

Have you been the victim of a product that makes exaggerated claims? Launch a complaint!

US visitors should submit a complaint to the US Federal Trade Commission!

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PatenTrim Review: Is PatenTrim Thermodrenix's Little Brother?

As I began reading the PatenTrim sales pitch, I got a very real sense of "deja-review"—haven't I reviewed PatenTrim before?

After a little digging I realized... sure enough, I had. Except it wasn't called PatenTrim the first time I reviewed it; it was called Thermodrenix.

With a couple of tiny exceptions, PatenTrim is Thermodrenix—or Thermodrenix is PatenTrim, however you want to slice it.

What's the difference between the two products?

The main difference is the green tea content; Thermodrenix contains both the "regular" and de-caffeinated versions, while PatenTrim contains only the decaffeinated stuff. In place of the "regular" green tea, PatenTrim contains Chromate™.

What makes me think the two products are produced by the same manufacturer are the sales pages; they are very similar, often using the exact same wording in the ingredient descriptions.

Both contain lots of happy horsecrap about not using doctored "before and after" photos and both stress the importance of using ingredient dosages reflective of positive clinical studies. Neither one reveals a "brick and mortar" contact address or who is really behind the manufacturing of the products.

Like Thermodrenix, PatenTrim also offers a totally-ambiguous, non-quantified statement regarding the benefits of the product...

"A slimmer you in 7 days, guaranteed!

Believe it or not, this is probably a smart move. Since all the ingredients in this formula are backed by clinical data, it would be a pretty simple task to disprove any ridiculous claim.

In a nutshell... manufactured claims are too easily dispelled, and realistic ones aren't likely to entice the visitor (would you be excited by a product that promised to shed 10 pounds in 2 months, even if it were an accurate assessment of the product's capabilities?).

That's why they are using statements like this.

To be fair, it's not that PatenTrim doesn't offer benefits—should the ingredients on the label be an accurate representation of what's in the bottle, it should offer some. It's just that they aren't exactly "rip roaring."

In addition, PatenTrim is very expensive. You can experiment with the relevant doses of the better ingredients in this formula for less than half the cost of this product.

With that said, let's have a look at the PatenTrim formula...

First of all, it's important to recognize that despite all the talk of "clinical trials", no peer-reviewed studies have been performed on PatenTrim; just some of the ingredients. As our scientific and technical advisor Elissa put it...

Most people would think, "proven ingredients = proven supplement blend" but this there are some unproven assumptions underneath this assessment.

For starters, when it comes to supplements, 1 + 1 does not always equal 2. In other words, if taking compound A results in X surplus pounds of fat lost; and taking compound B results in Y surplus pounds lost, taking A + B does not necessarily result in a loss of X + Y pounds. Ultimately, all the different pathways converge: so pushing the system from multiple directions doesn't guarantee a superior result.

Likewise, it's assumed that there is no conflict between the different compounds, and that there's a linear relationship between short and long term results (i.e., a compound that results in - say - 5 extra pounds lost in a 6 week period, means 10 extra pounds should be lost in 12 weeks, 15 pounds after 18 weeks, and so on).

OK, now let's take a closer look at the ingredients...

1) SuperCitrimax: A single serving of PatenTrim provides 1,400 mg of SuperCitrimax, meaning a full day's serving (2,800 mg) correlates to the amount used in the positive clinical study (see J Med. 2004;35(1-6):33-48). That's good.

Don't get too excited though; if you check the study, you'll see that individuals participating were restricted to 2,000 calories per day. They also walked 30 minutes per day, 5 days out of 7.

Total weight lost?

An average of 5.4% in bodyweight over the course of 8 weeks. A two hundred pound man would have lost 10.8 lbs., or 1.35 lbs. per week. That's well within the realms—actually probably less— than what you can expect to accomplish on your own with a more rigorous training program and a slightly more restrictive diet.

2) Chromate™: A patented version of niacin-bound chromium, this is a pretty standard and cheap addition to many weight loss products. Although chromium polynicotinate is probably the best form of chromium to experiment with, evidence validating its weight loss characteristics are preliminary. Other forms of chromium have not fared so well in studies (see the full review for more information and clinical references).

3) Green tea: PatenTrim contains 1,000 mg of decaffeinated green tea, standardized for a critical catechin, EGCG. However, while studies have shown that while EGCG is beneficial to dieters, it really needs to be combined with caffeine and the other catechins naturally present in green tea to offer the greatest fat burning benefits (Journal of the American College of Nutrition, Vol. 26, No. 4, 396S-402S).

4) Forslean® (coleus forskohlii): The patented version of coleus forskohlii, a cAMP stimulators. Camp is a "cellular regulator." In other words, this compound is required to "spark" many intercellular processes. An increased concentration of camp can have such "total-body" effects as raised thyroid hormone levels and increased fat burning.

While the effects of coleus forskohlii and a corresponding positive effect on weight loss have been established in one study (Journal of Obesity Research August 2005, "Body Composition and Hormonal Adaptations Associated With Forskolin Consumption In Overweight and Obese Men"), the results were not overwhelming.

Another study was less positive (Journal of the International Society of Sports Nutrition. 2(2):54-62, 2005). It concluded...

"Results suggest that CF (coleus forskohlii) does not appear to promote weight loss but may help mitigate weight gain in overweight females with apparently no clinically significant side effects."

5) Gymnema Sylvestre extract: In the correct dosage, preliminary evidence seems to indicate this ingredient may affect blood glucose levels by reducing its absorption in the intestines. More evidence is needed to properly rate the effectiveness of this ingredient as a potent fat burner. It also may inhibit the ability to "taste" sweet or sour flavors. According to the PatenTrim web site...

"Gymnema, when combined with Super Citrimax, was extremely effective in helping subjects lose fat, decrease their appetite, and increase fat oxidation."

Uh, not really. When you review the specifics of the study, you'll see that it was performed with a combination of SuperCitrimax, 400 mg of Gymnema (there's only 250 mg in this formula) and niacin-bound chromium, and compared to SuperCitrimax used in isolation. There was not a dramatic difference between results attained by the study participants using the combination of ingredients and those simply using SuperCitrimax.

PatenTrim should either contain a full 400 mg of gymnema (to make it compatible with this study), or it should simply leave out the gymnema altogether.

6) Bioperine: A common ingredient to many supplements, its role is to enhance the bioavailibility of certain supplements through increased absorption. See the full review for more details.

Alright, now that we've been through the ingredient list, what is the bottom line?

Frankly, it's not that the PatenTrim formula is a bad one. SuperCitrimax is a helpful, but not earth shattering ingredient, and it's present in the correct dosage. Green tea standardized for EGCG is nice, but would PatenTrim would fare better with regular, "caffeinated" tea. Gymnema and Forslean don't add much to this formula, but they don't detract from it either. It ain't a revolution in a bottle by any means, but it's not bad either.

So what are the problems with PatenTrim?

First and foremost, the price. $70 is an outrageous price for a product like this. For example, here's what you could buy at a reputable online retailer like BodyBuilding.com for under $35...

This would allow you to experiment with the appropriate doses of the more promising ingredients in PatenTrim, and still have over $30 left to take a friend out for lunch! At $35-$39, PatenTrim might be worth experimenting with, if you could confirm the retailer was genuine and that you would have a positive purchasing experience. But at this price, it's not worth purchasing.

The second problem with PatenTrim?

Whenever supplement companies nearly fall over backwards in an attempt to convince me how honest they are, I get a bit worried. All it does, in my opinion, is raise doubts in my mind. But I'm a suspicious bugger, and I may be wrong. So here's where you can weigh in and help...

To read or leave feedback on PatenTrim,
please click here!

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Labrada's Xhilar8 Thermotropic Fat Burner Review

I've been a fan of Labrada weight loss products since the original ephedra-based Charge came on the market some years back (it was my all time favorite ephedra product!). So I was excited to check out Labrada's newest weight loss offering, "Xhilar8".

Xhilar8 is described as a "thermotropic" fat burner, which is basically a combination of a "thermogenic" (i.e., a fat burner) and a "nootrophic" (i.e., a product that enhances mental focus and acuity, mood and clarity). According to Labrada, this formula...

"... helps combat stress and promote a feeling of well being, while releasing fat to be burned immediately for energy."

What's in it? Well, a single, daily, 3-capsule dosage contains...

Iodine (125 mcg, from kelp): Iodine is used by the thyroid gland to make the various thyroid hormones necessary for optimal performance. Low or sluggish thyroid performance can lead to low energy levels or overweight.

Of course, iodine supplementation is only helpful if you actually have low levels of thyroid hormone. If you are not iodine deficient, kelp may possibly induce hyperthyroidism. According to the Natural Database, "prolonged, high intake of dietary iodine is associated with goiter and increased risk of thyroid cancer.

... plus a proprietary 2072 mg blend of the following...

L-Tyrosine: an amino acid precursor of several important neurotransmitters -- l-dopa, dopamine, norepinephrine, and epinephrine -- which are important contributors to mood, cognitive performance, as well as combating stress.

There is plenty of clinical evidence showing l-tyrosine plays such a role, although most studies I have reviewed used much higher doses than is included in this formula (see Aviat Space Environ Med 1995;66:313-9 Brain Res Bull. 1994;33(3):319-23, Brain Res Bull. 1999 Jan 15;48(2):203-9, Pharmacol Biochem Behav. 1999 Nov;64(3):495-500).

L-Taurine: An amino acid that plays a number of important physiological roles, including neurotransmission and / or neuromodulation. High dose experiments with rats and mice have shown that taurine can influence mood/behavior by acting as an "anxiolytic"—meaning that it reduces anxiety.

Clinical trials in humans for controlling manic symptoms in subjects with bipolar disorder are currently being conducted, but there is little data available yet. At this point, it's not known if taurine has nootropic activity in humans at the doses commonly seen in energy drinks or other stimulant supplements (1–3 g).

Rhodiola Rosea: An adaptogenic herb used in Russian folk medicine. Positive effects on physical/emotional have been documented in several animal studies and small human clinical trials. Effective dosage is somewhere between 340 - 680 mg/day. Although we can't determine exactly how much rhodiola is in Xhilar8, it is certainly possible it contains a potent dose. 200 mg Caffeine (anhydrous): On its own, caffeine is a decent thermogenic with demonstrated benefits for weight loss (see Am J Clin Nutr. 1989 Jan;49(1):44-50, Am J Clin Nutr. 1980 May;33(5):989-97), although some data indicates it offers greater benefits to lean individuals that those who are overweight (see Am J Physiol. 1995 Oct;269(4 Pt 1):E671-8).

The combination of caffeine and green tea present in this formula is a good one, and encourages even greater weight loss (see Obes Res. 2005 Jul;13(7):1195-204).

Thiamine disulfide diisobutyrate: Thiamine, also known as Vitamin B1, plays an important role in energy metabolism, and is thought to play a role in appetite suppression. This novel, potent version of thiamine is being touted as a potent enhancer of physical and mental energy—especially when combined with caffeine (as it is in this formula). Green tea: One of the few "bright lights" for weight loss, green tea has several demonstrated effects beneficial for weight loss. Unfortunately, we can't be sure how much green tea is included in this formula, or for what percentage of vital catechins it is standardized. I would venture to guess it is not an optimal dosage, simply because it is listed behind both caffeine and thiamine on the label (ingredients are listed in order of dosage, from highest to lowest). That said, it remains possible this formula contains enough green tea to provide benefits... especially since it is combined with caffeine. Kola nut powder: Animal studies have shown kola nut has fat burning properties, but for humans, the main benefit kola nut offers is as a diuretic and a source of caffeine (kola nut can contain between 2-4% caffeine). Guarana seed: Included in fat burners for its caffeine content. Probably only a minimal amount included in this formula, providing no major benefits. Cayenne pepper: Although the label doesn't indicate it, cayenne is probably included here because of its capsaicin content -- it's the chemical that gives chile peppers their "heat." The theory is that capsaicin "revs" up your metabolism by creating heat, thus burning off extra calories. However, this study (Am J Physiol Regul Integr Comp Physiol. 2007 Jan;292(1):R77-85. Epub 2006 Jul 13) says it best... "Capsaicin has been shown to be effective, yet when it is used clinically it requires a strong compliance to a certain dosage, that has not been shown to be feasible yet."

In other words, in order for capsaicin to have an effect on your metabolism, it has to be taken in doses much too high to make it practical.

Glutamic acid: An amino acid and an abundant excitatory neurotransmitter. It also plays a role in celular metabolism. Difficult to assess what value it adds to this formula when the dose is not revelaed. Likely here only as "label dressing."

As you can see, some of the critical ingredients—like tyrosine and taurine—are very definitely under-dosed. Other critical ingredients—like green tea and the novel form of thiamine—may be under-dosed, but it's really impossible to know for sure with this proprietary formula.

The remainder of the formula—kola, guarana, cayenne and glutamic acid—probably don't add much other than a little extra hit of caffeine to this formula at the dose they are included in.

Bottom line on Xhilar8?

Labrada claims this is a product that enhances mental clarity and focus and combines that with powerful fat burning.

I would argue that the mental clarity element of this formula "trumps" the fat burning element; the majority of ingredients present at useful doses have this as a focus.

It's really only the caffeine and the green tea that provide the "fat burning" element of this formula, and it's impossible to asses the potency of the green tea here, and therefore its value to the formula.

That said, I did have the opportunity to experiment with the Xhilar8 product. Given that my comments are anecdotal, I really enjoyed it; it gave me a nice smooth boost without any jitters. I found myself relaxed and focused and I did not experience a "crash." I took it with breakfast with a glass of water as recommended and found my mornings to be focused and free of distraction.

In other words, I really liked this product. I'm not convinced fat burning is its "forte", but it's awesome for focus and concentration. If this is what you are looking for in a product, I certainly would not hesitate to recommend giving it a try.

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Zylotrim Diet Pill Review: What's The Scoop With Zylotrim?

A few visitors have contacted us about Zylotrim, wondering if there was anything to the hype behind this product. Now, we don't normally review every single product that a visitor inquires about. We simply don't have the resources. However, after doing a couple of searches on Google to see the what the other "review" sites were saying, I though it would be worthwhile to review Zylotrim—because no one has actually got it right yet.

Zylotrim is produced by the infamously nefarious "Obesity Research Institute", a company that has incurred the wrath of the Federal Trade Commission on several occasions for making false and unsubstantiated claims (see more on the FDA action here).

A visit to the official Zylotrim web site does nothing to re-instill confidence in this company; no company information is provided, the ingredients are revealed as a special South American "yam" extract, and a slick and polished video plays a typical "weight loss" message that has exactly zero scientific credibility.

Fortunately, Walgreens stocks Zylotrim, so it was relatively easy to confirm that the active ingredient in Zylotrim is 3-Acetyl-7-Oxo-Dehydroepiandrosterone, normally referred to as 7-Keto DHEA, or simply, 7-Keto.

7-Keto is a metabolite of DHEA. DHEA is a steroid hormone produced naturally by the bodies of both men and women.

The good thing about 7-Keto is that it displays no apparent side effects (i.e. no conversion to testosterone or estrogen, and no effect on the sex hormones). In other words, it doesn't "act" like a typical steroid.

What's promising about this ingredient is its positive effect on thyroid hormone levels in obese people -- again, without any adverse effects of any kind. And yes, there is a small amount of clinical data to validate this! (see Journal of Exercise Physiology, Volume 2, Number 4, October 1999, J Nutr Biochem. 2007 Sep;18(9):629-34. Epub 2007 Apr 5, Current Therapeutics, (7):435-442 2000).

The dosage for these studies was 100 mg, given twice a day. And yes, a single two-capsule dosage of Zylotrim contains 100 mg.

So, as unbelievable as it may seem, there actually is some merit to Zylotrim. The main problem I have with this product (other than the fact it is a manufactured by company that has shown complete disdain for its customers) is that it is extremely expensive.

For instance, the Walgreens information reveals that a single bottle of Zylotrim contains 15 2-capsule servings. That's 30 caps. At the time of this writing, they are selling this product as a two-bottle bonus pack, so you end up getting 60 caps for $24.99.

If you plan to take Zylotrim at the dosage shown effective in the clinical references I mentioned above, you will need to take 2 caps, twice daily. At 4 caps per day, those two bottles will last you exactly 15 days. You'll need 4 bottles—an investment of $50—to get you through the month.

As an alternative, you can buy a month's worth of the NOW brand 7-Keto from BodyBuilding.com for $19.99... a $30 savings.

Bottom line?

7-keto is no weight loss miracle, but current clinical data indicates it may provide some benefit at the appropriate dosage. It's up to you if you think it warrants an experiment. It's probably worthwhile if you're paying $20 for a month's supply. Not sure I'd bother with Zylotrim though... it's expensive, and produced by a company with "questionable" ethics.

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Biogenix Therm Acai Review: An Antioxidant Fat Burner?

I must admit I was feeling a bit tired and worn out when I took my first look at Therm Acai. That's why I had to rub my eyes, shake my head, and re-read the product advertising to make sure I wasn't dreaming. Sure enough, I wasn't...

"Therm Acai is an effective and powerful antioxidant fat burner! The quality ingredients used for internal fat loss are what make this product effective. The Acai present in Therm Acai will help your body lose the excess fat buildup."

Wow. This isn't just nonsense, it's outrageous nonsense. Acai-based weight loss solutions have been circulating around on the Internet for some time now (usually sold through "negative option billing programs") and have even attracted the attention of the law. Connecticut Attorney General Richard Blumenthal had this to say about the common Acai scams...

“There are no magical berries from the Brazilian rainforest that cure obesity — only painfully real credit card charges and empty weight loss promises. Aggressive acai berry pitches on the Internet entice countless consumers into free trials promising weight loss, energy and detoxification. These claims are based on folklore, traditional remedies and outright fabrications–unproven by real scientific evidence."

Yep, he's right. While acai is a decent antioxidant with certain beneficial characteristics (see the acai review for full details) there is absolutely ZERO evidence it has any weight loss properties, nor that it is significantly more valuable than cheaper and less exotic antioxidant fruits (blueberries, pomegranates, concord grapes, etc.).

Well, maybe the other ingredients in Therm Acai will redeem it (you think?) What else is in it?...

Green Tea Extract (200 mg) Green tea is one of the few weight loss supplements that shows great promise and has some decent clinical evidence validating its effects. However, its effectiveness is largely dependent upon its potency, dosage, and whether it is standardized for the appropriate catechins. It's impossible therefore, to assess the true value green tea adds to this formula. Garcinia Cambogia (100 mg): Standardized for 50% hydroxycitric acid, an ingredient many thought would prove as effective a diet and weight loss aid to humans, as it appeared to be to animals. Not so. An early study published in the Journal of the American Medical Association (JAMA. 1998 Nov 11;280(18):1596-600) indicated that hydroxycitric acid has no positive weight loss effects, concluding... "Garcinia cambogia failed to produce significant weight loss and fat mass loss beyond that observed with placebo."

Caffeine (50 mg): Not surprising to find this here—caffeine has a well established record as a mild thermogenic, and does deliver mild weight loss results (see Am J Clin Nutr. 1989 Jan;49(1):44-50, Am J Clin Nutr. 1980 May;33(5):989-97).

It also cheaply and effectively addresses the most common complaint of dieters; lack of energy. This is a relatively low dose however, as most fat burner supplements contain 2-4 times this amount. Unless you are someone who does not drink coffee or caffeinated beverages on a regualr basis, it's unlikely you will feel much of a boost from this product.

Apple cider vinegar: An age old weight loss "scam" there is no evidence apple cider vinegar helps with weight loss, although it appears to delay gastric emptying and improve insulin function in diabetics. Kelp: Seaweed or kelp is found in many fat burners because of its iodine content. Iodine is used by the thyroid gland to make the various thyroid hormones necessary for optimal performance. Low or sluggish thyroid performance can lead to low energy levels or overweight.

Of course, iodine supplementation is only helpful if you actually have low levels of thyroid hormone. If you are not iodine deficient, kelp may possibly induce hyperthyroidism. According to the Natural Database, "prolonged, high intake of dietary iodine is associated with goiter and increased risk of thyroid cancer.

Grapefruit: Because of the ambiguous nature of the way this ingredient is labeled, it's difficult to assess its role here. Is the grapefruit powder standardized for narinigin? After all, naringin is often included in products to enhance the bioavailability of ingested nutrients/nutraceuticals, although specific benefits have not been demonstrated.

It also has cholesterol-lowering effects, and can affect drug metabolism. Grapefruit seed extract, on the other hand, has anti-microbial properties; nothing wrong with that, of course, but not a valid reason for its inclusion in this product.

And there you have it, Therm Acai in a nutshell. Despite the less than postive review, Therm Acai is pretty cheaply priced; $9.99 for 60 capsules at BodyBuilding.com. It's too bad that we don't know a little more about the green tea in this formula—if standardized for the appropriate amount of EGCG, Therm Acai would be a decent low cost green tea / caffeine fat burner (studies show the combination of caffeine with green tea is helpful for weight loss).

Since we don't know, it's impossible to make the call.

Have you used Therm Acai? Share your
comments and read Therm Acai user reviews / testimonials, click here!

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Review: Gaspari Nutrition's Spirodex Fat Burner

According to the product advertising, Gaspari Nutrition's Spirodex is...

"Guaranteed to provide you with an intense feeling of mood enhancement, mental clarity and energy."

Although Gaspari also claims Spirodex will help "suppress appetite", they really don't make much in the way of claims regarding the weight loss abilities of the product—which, quite frankly, is pretty refreshing. As you no doubt are aware, most manufacturers can't prove their products have the "fat blasting" powers they claim.

Unfortunately, that doesn't prevent them from making those claims.

So this is a refreshing change, and an encouraging one; Gaspari has a reputation for making class-leading products (although they are not above engaging in scummy behavior) and it's nice to see they aren't lowering themselves to the level of their competitors by "ratcheting up" the outrageousness of their advertising..

That said, Spirodex doesn't "look" like your typical "off the shelf" fat burner. The small, compact bottle looks like it would be more at home occupying a shelf behind the counter at your local pharmacy—in other words, it looks like a prescription medication.

Which, of course, it is not.

So with all that said, what's in Gaspari's new offering?

Oxytropis falcata extract: Misspelled in the Gaspari advertising as "Oxytropis falcate" (also known as "locoweed"), this is a toxic Chinese plant of the bean / pea / legume family that has been used in ancient Chinese medicine for centuries as an anti-inflammatory—there is some evidence to support its usage.

It's also a rich source of numerous flavanoids including kaempferol, quercetin and chrysin.

According to Gaspari, this element of the formula is standardized for "biogenic amines" (in "cognition supplements" like this one, this often refers to neurotransmitters), although they do not reveal which one(s) or to what potency they are standardized.

That turns out to be a problem, because discovering which "biogenic amines" O. falcata might be standardized for is difficult, as the English studies I located discussed its flavanoid content solely, while other studies discussing its constituents were published in Chinese. However, our intrepid scientific and technical advisor Elissa dug up this translated dissertation abstract which indicates O. falcata is a source of several substituted phenylethylamines.

Once again, it's impossible to confirm exactly which—if any—phenylethylamine (PEA) derivatives are included here (phenylethylamine is the amphetamine-related chemical commonly found in chocolate. It is rapidly metabolized by the enzyme monamine oxidase (MAO), which makes oral supplementation pointless unless it's accompanied by an MAOI (monamine oxidase inhibitor) or two).

Nonetheless, PEA is an ingredient Gaspari likes to "play" with; both their CytoLean (now discontinued) and CytoLean V2 fat burners contain it and a series of MAOIs. This isn't necessarily a good thing. As Elissa noted in a correspondence with me about Spirodex...

"The family of phenylethylamine-derivatives contains some pretty scary members. And there appears to be very little information available on either the pharmacology or toxicity of these derivatives. I feel it's irresponsible for Gaspari to be playing "guessing games" with its customers over the ingredients in this product."

We're looking into O. falcata in greater detail to see if we can't reveal a little more about its constituents and how it may impact this formula. Stay tuned!

Camellia sinensis: Quite simply, Chinese tea. Since many teas are actually harvested from this species (including green, oolong, and black teas) it's impossible to know which tea we're dealing with here. Both oolong and green tea show benefits for weight loss, for example. This element of the formula is not standardized for EGCG, as is the green tea in most weight loss supplements. That likely diminishes the value of the tea in this formula.
Hordenine: A biogenic amine found in a number of plants, hordenine is often included in weight loss supplements, largely because of its ability to stimulate norepinephrine release (there's zero documented proof to confirm this, however!). In this formula, hordenine may play a different role. Because it also acts as a highly selective substrate for MAO-B, it may prevent the quick metabolizing of the phenylethylamine derivatives we're assuming are included in the formula. Once again, it is impossible to know for sure. Geranium maculatum extract: Also known as "Wild Geranium" or "Spotted Geranium." Geranium extracts are pretty popular in both weight loss supplements (see OxyElite Pro) and preworkout formulas (see USP Labs' Jacked) for the incredible boost of energy they provide. While most retailers are labeling their geranium extracts as DMAA or 1-3 dimethylamyamine, Gaspari has labeled theirs as "4-methylhexan-2-amine", which happens to be exactly the same compound. While geranium extracts are potent CNS stimulators, there is zero credible documentation that they facilitate dramatic weight loss.

Incidentally, DMAA has been added to the World Anti Doping Agency 2010 prohibited list, so if you're a competitive athlete, you'll want to avoid this product.

Paullinia cupana (standardized for purine content): This is more commonly known as "guarana". Its purine content, in this case, is likely caffeine. Two thumbs down to Gaspari for needlessly complicating the label and making their product seem more "advanced" than it actually is. Caffeine: No surprise here; caffeine graces the label of most stimulant based weight loss supplements on the planet. Caffeine's benefit as a mild thermogenic is well documented (see Am J Clin Nutr. 1989 Jan;49(1):44-50, Am J Clin Nutr. 1980 May;33(5):989-97), and some evidence indicates that when combined with green tea (as it may be here) it elicits somewhat greater fat burning effects (see Obes Res. 2005 Jul;13(7):1195-204).

Of course, caffeine also gives most people a much needed "boost" of energy to help them get through their day.

So there you have it; Spirodex in all its "glory."

How's it measure up?

Well, since the only claims Gaspari really makes for Spirodex are that it will provide you with mood enhancement, mental clarity and energy, plus a bit of appetite suppression, it's hard to argue that this product won't deliver on those promises.

The simple combination of DMAA and caffeine will provide you with plenty of energy. For many people, a hearty dose of caffeine is all that's needed for mental clarity and "mood enhancement"... same deal for mild appetite suppression.

It's the Oxytropis falcata extract that's the wild card here.

As addressed earlier, we don't know if and or which phenylethylamine derivative(s) it is standardized for, and that's a problem, as there is very little information available on either the pharmacology or toxicity of these derivatives.

In other words, there's a potential for danger here, and it's irresponsible of Gaspari not to be more forthright with its customers about the true nature of all Spirodex's constituents.

For that reason, this is not a Gaspari offering we can heartily recommend.

We'd love to hear from users though; how did you like the product? How did you feel?...

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SomnaSlim Review: The Best Night Time Diet Pill?

"Lose weight in your sleep", boasts the advertising for the night time diet pill SomnaSlim, "or get your money back, guaranteed!"

Wow! Now that's taking the whole "losing weight is easy" thing to an entirely new level.

Nonetheless, it's not difficult to see why such claims such as this one manage to ensnare customers. It is, after all, an appealing thought; as you sleep comfortably, SomnaSlim's unique blend of herbs works unobtrusively in the background, incinerating fat and transforming your body into a lean, mean, sexy machine. A night time diet pill? Lose weight while you sleep? Where do I sign up?

Of course, this is nothing but fantasy. Both your metabolic rate and your caloric requirements are at their lowest when you're sleeping. And there is no miraculous blend of herbs that is going to crank up some internal fat burning furnace while you're dreaming of hot fudge sundaes and endless buffets.

But what about a product that helps you sleep better? Will that help you lose weight? After all, in the SomnaSlim FAQs it states...

"Did you know that there is a correlation between not enough sleep and gaining weight? Somnaslim will help put you to sleep and burn fat...at the same time!"

Well, there is a study (Arch Intern Med. 2005 Jan 10;165(1):25-30) that does confirm that reduced amounts of sleep is associated with overweight and obese status.

However, the authors of this study torpedo the SomnaSlim statement when they state...

"We caution that this study does not establish a cause-and-effect relationship between restricted sleep and obesity. Investigations demonstrating success in weight loss via extensions of sleep would help greatly to establish such a relationship."

Ooops. I guess the SomnaSlim retailers either missed this, or decided to conveniently overlook it.

That said, is there any merit to the SomnaSlim formula? Let's have a look at what's in it...

Garcinia cambogia (200 mg): Standardized for hydroxycitric acid, an early study published in the Journal of the American Medical Association (JAMA. 1998 Nov 11;280(18):1596-600) indicated that hydroxycitric acid has no positive weight loss effects, concluding... "Garcinia cambogia failed to produce significant weight loss and fat mass loss beyond that observed with placebo."

Melatonin (2 mg): An antioxidant, this ingredient is well known for its role in sleep regulation.

Plus a 1200 mg strong blend of the following...

Valerian root: Commonly recognized for its use as a natural sleep aid, although research suggests it appears to work best when used in conjunction with hops. Glucomannan: A fiber supplement that has shown benefits for weight loss, albeit at much higher doses than what is included in this product. Decaffeinated green tea: Green tea, because of its unique blend of EGCG, caffeine, and various other polyphenols, happens to be a pretty useful weight loss supplement. However, to my knowledge, all studies validating green tea's effects on weight loss have been performed on versions containing caffeine. There is no proof decaffeinated versions work anywhere near as well. In fact, because of caffeine's well-established effects on the CNS, we can be nearly positive that it does not. Aloe Vera: The SomnaSlim web sites states "there are too many benefits of Aloe vera to list them all here." Really? While preliminary research data indicates it may offer additional benefits, the only truly established one is the one you already know about; the benefit it offers your skin when used topically. Passion Flower: A mild sedative and sleep aid. Phase 2: Advertised as a "carb blocker", a recent UCLA study on Phase 2® concluded... "Clinical trends were identified for weight loss, inches lost from the waist, energy, and decrease in triglycerides, although statistical significance was not reached. The reason that significance was not achieved was the small number of subjects who completed the study and the wide variability of the results within each group. Further studies with larger numbers of subjects are necessary in order to definitively demonstrate effectiveness."

Whoop-dee-do. Hardly a weight loss miracle.

Chitosan: advertised as a fat blocker, clinical data shows chitosan offers little to no weight loss benefits (see Int J Obes Relat Metab Disord. 2004 Sep;28(9):1149-56, Cochrane Database Syst Rev. 2005 Jul 20;(3):CD00389, Singapore Med J. 2001 Jan;42(1):6-102, J Am Coll Nutr. 2006 Oct;25(5):389-94). Gymnema: In doses of 400 mg per day (many times what is included in this product) gymnema has demonstrated antidiabetic effects. Animal studies also indicate it may inhibit the ability to taste sweet or bitter. 5-HTP: Often used as an alternative treatment for depression. At high doses (900 mg/day) it has been shown to help improve appetite control and weight loss. In this formula, it is unlikely to be present as any more than "label dressing" dosages.

As you can see, the bulk of the SomnaSlim ingredients included to encourage weight loss either have not been proven to do so at all, or are present in dosages far below what has been proven useful in published clinical studies. As a weight loss product, SomnaSlim is a bust.

Frankly, the value of this formula lies with the melatonin and valerian root combination, which will probably help most people sleep more soundly. Despite this, there are still two major problems with SomnaSlim...

It is retailed by an anonymous company. We're not fans of companies who do not reveal who they are; there's only one good reason for not doing so, and that's to avoid accountability to the consumer. How can you get a refund from a company if the only information they provide to you is an e-mail address that they can ignore as they wish? $15 a bottle is incredibly expensive when you consider that you can buy a three month's supply of melatonin and a three month's supply of valerian root for less than $10 at a reputable online retailer.

At the end of the day, the take home message here is a simple; there is nothing in this formula that justifies it being advertised as a "night time diet pill."

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Healthé Trim Fat Burner Review & Information

If you're old enough, you might remember the movie "Valley Girl," which glorified 1980's teen "air-headedness". While I never I saw it myself, I remember a few girls in high school who adopted the vernacular, and it was the first thing I thought of as the web site for Healthé Trim popped up, and "Monique" began her speil...

Like OH MY GOD, wouldn't you just, like, love to get high school skinny again?

Uh... right, Monique.

First of all, I highly doubt you've ever had a weight problem. And secondly, how many years has it been since you've been in high school... like, uh, maybe three? Like whatever, Monique.

Thankfully, I was able to turn Monique "off", and have a closer look at Healthé Trim in peace and quiet. On the face of things, Healthé Trim seems like a winner. Although it makes the usual outlandish claims—that it will help you lose weight fast, curb your appetite, boost your metabolism while providing a long lasting boost of energy—its effectiveness appears to be backed by both a clinical study and a bona fide medical doctor's recommendation.

Let's take a closer look at the study...

To begin with, this study does not appear to be published in any journal that I could find.

So as far as I can tell it is not a peer-reviewed, published study.

What's the significance of this?

Well, when the people who have the most to gain financially from a positive outcome of a study are the same ones who are conducting it, it pays to be skeptical.

It doesn't necessarily negate the results, but until the study's methodology has been critiqued by credible professionals, it has minimal value indeed.

Secondly, what study parameters are revealed indicate this is a very "loose" study indeed. For example, study participants were asked not to change their daily eating regimen. What this essentially does is put every single person into their own unique study group, since each individual is going to be consuming a different number of calories each day.

Some people will eat more (or less) than others. Subconsciously, some may see the fact that they are taking a supplement as a reason to eat less. Others may see the pill as a license to eat more. And thus, it makes it very, very difficult to attribute any real value to the supplement since there are too many variables present to make a conclusive statement about its effectiveness.

And what about the "doctor" recommendation also so highly touted?

It appears that Dr. Michael Carroll is an Atlanta-based immunologist who wrote a diet book back in 1996 called "Be Fat Free Forever." According to the Healthé Trim web site, a friend introduced him to the product after losing "25 lbs. in 4 weeks" and now he's an avid fan, prescribing it regularly in his weight loss clinic. I'll let Dr. Carroll take it from there...

"... HealtheTrim is made in a pharmaceutical grade facility to ensure purity and quality control.  Each of the ingredients in HealtheTrim had individual research backing up their individual claims concerning their various biological activities.  What impressed me the most was the formulators of HealtheTrim not only chose the most appropriate ingredients to get the results they were looking for, but they created an effective blend or mix taking several years of testing before making the product available to the public. This was the confirmation I needed to begin using it with my patients in my weight management clinics."

Sorry doctor, but I'd like to take issue with you on a few points...

"Each of the ingredients in HealtheTrim had individual research backing up their individual claims concerning their various biological activities."

Really? It seems you and I must be looking at different versions of Healthé Trim then. For instance, where's the peer reviewed, published data that validates hoodia's ability to curb appetite and enhance weight loss? That pyruvate, in the dosage provided in this product, enhances weight loss, decreases appetite and increases energy? Some of the latest data I have seen isn't particularly positive. And that's at a 2,000 mg dosage! And what about chromium? It's hardly a weight loss miracle.

Next, this statement just doesn't pass the smell test...

"...the formulators of HealtheTrim not only chose the most appropriate ingredients to get the results they were looking for, but they created an effective blend or mix taking several years of testing before making the product available to the public."

You're telling me that instead of getting this product to the market immediately and starting to make money, the makers of Healthé Trim spent a couple of years piddling around testing the product—when they are not obligated by law to prove their product works as claimed? Even in-house studies are prohibitively expensive, and no one—short of the big drug companies—could afford to spend years running tests, reformulating, and testing again. And if they were really serious about demonstrating their product worked, they wouldn't have used such loose study parameters in the one so prominently presented on the sales page (as discussed above).

Sorry, but I don't buy it.

Before I even begin dissecting the ingredients, let's address another major problem. There are 16 ingredients in this formula. This might sound impressive, but here's the issue; just like pharmaceutical drugs, the "natural herbal" ingredients in weight loss products must be present in an appropriate dosage to have any effect. The makers of Healthé Trim are not revealing either the amount of total ingredients in the formula, or the amount of each individual ingredient (or even to what extent each ingredient is standardized, if it is at all).

Thus, it's impossible to effectively assess the impact of each ingredient on the formula. However, some basics logistics can tell us a lot. For example, the largest capsule size generally used by retailers and well-tolerated by consumers is "00".

The exact amount of ingredient such a capsule can contain depends on the density of the powdered ingredient, but a good general number is 650 mg.

So the greatest amount of active ingredient we can expect from this product is in the 1300 mg range (from a 2-cap dose).

Unfortunately, that means that the majority of the ingredients will only be present as "label dressing" (i.e., they make the label look impressive, but they do nothing for the effectiveness of the formula).

With that out of the way, let's have a look at the formula...

1) Resveratrol: A powerful antioxidant with possible anti-aging effects. From our review...

"While resveratrol shows a great deal of promise, questions remain about its utility in humans, as oral bioavailability is low and human clinical data is still lacking...pilot studies are just beginning."

2) Chromium picolinate: A trace mineral that plays an important role in proper insulin function, clincal data shows chromium to have minimal, if any effect on weight loss.

3) Green tea leaf extract: There's no doubt green tea is one of the no-brainer ingredients that shows some real promise for dieters. It is, of course, if it's present in a strong enough dose, and standardized for the appropriate catechins. Is it in this case? Your guess is as good as mine.

4) Hoodia gordonii: Despite all the hoopla about hoodia, the P57 molecule, and its amazing appetite suppressing qualities, no published clinical data validates this ingredients effects. Additionally, there are some real problems with supply and demand that suggest most hoodia products are counterfeit. Add the fact that Unilever curtailed its development of a hoodia product in 2008, and you've got to be skeptical. See the full hoodia review for complete details.

5) Caralluma fimbriata: An Indian cactus, there is a small amount of clinical data showing that 1,000 mg of Caralluma taken once a day for 60 days can suppress appetite and reduce weight circumference. It's a bit hard to believe there's a 1,000 mg of ingredient here, considering a 2 capsule dose is likely to only deliver 1300 mg or so, and there's 15 other ingredients in this formula.

6) Coix seed: Also known as Job's tears and used in traditional Chinese medicine for ages there is some early evidence this annual plant may have cancer fighting characteristics. More importantly for our purposes, a coix seed extract has been shown to have the ability to inhibit fatty acid synthase in rats.

Fatty acid synthase is an enzymatic system that is involved in the process of turning carbohydrates into fat. Early animal studies suggest the inhibition of fatty acid synthase can lead to dramatic weight loss.

7) Poria cocos: A fungus used in traditional Chinese medicine, there is some evidence this ingredient may have anti-cancer benefits and may also act as an anti-inflammatory. Nonetheless, very little western research has been performed on Poria cocus.

8) Cassia seed: Probably referring here to Cassia nomame, since it is often included in weight loss products for its "ability" to inhibit the enzyme lipase which is required for the break down and deposit of fat. However, there's very little clinical evidence to validate these claims. Check out this excerpt from this Pubmed abstract on "Nutraceutical resources for diabetes prevention"...

"There does not appear to be a natural lipase inhibitor functionally equivalent to orlistat, although there are poorly documented claims for Cassia nomame extracts." (Med Hypotheses. 2005;64(1):151-8.)

9) Lotus leaf: Um... when you're eating Dim sum, these are used to roll up your "sticky rice." Can't see any other good reason for this to be included here.

10) Water plantain: Also known as Alisma, this ingredient is likely included here for its diuretic action.

11) Cumquat: Kumquats are small fruit bearing trees. The citrus fruit looks similar to an orange, but is much smaller and more oval in shape. This is a perfect ingredient to further illustrate the labeling issues with this product. For instance, the peel of the fruit is a rich source of essential oil, which contains numerous constituents. What element of kumquat is this formula standardized for? Is it a fruit extract? A peel? An oil? Who knows?

12) Methionine: This ingredient aids in fat metabolism and acts as an antioxidant.

13) Mulberry leaf: There is some evidence mulberry leaf may be helpful in the treatment of diabetes.

14) Gymnema sylvestre: a plant native to India, there is some evidence it can inhibit glucose uptake in the small intestine as well as showing potential anti-diabetic effects—at doses much higher than present in this product, of course.

15) Eleutherococus senticoccus: Also known as Siberian ginseng, this herb is known as an adaptogen (similar to ginseng). However, it is an unrelated species—and not similar to either Asian or American ginseng.

16) Pyruvate: A "gateway" compound in a process called the "Krebs" cycle (the "Krebs" cycle is the intercellular process in which glucose (sugar derived from carbohydrates), is converted into energy). There is some evidence it helps with weight loss, but only at an extremely high dose (the aforementioned study used 22-44 grams of pyruvate).

In addition, Healthé Trim contains as undisclosed amount of unidentified "trace" minerals.

After reviewing the mass of ingredients in this formula, I hope the main issues previously discussed "pop out" at you...

For many of the ingredients, there's little or no clinical evidence validating the claimed weight loss effects. Some ingredients, although interesting, seem to be added for impact rather than effect. It's not revealed how much of any of the ingredients is included in the formula, nor what they are standardized for, if they are at all. Because of the logistics of serving size, most ingredients are likely to be under-dosed.

Despite the clinical study and "doctor's recommendation" the onus is on the makers of Healthé Trim to step up to the plate and provide this information to you, the consumer. They haven't done so, and that, in my opinion, is a red flag worthy of some attention.

That said, this product is backed by a guarantee...

"If you are not fully satisfied with any HealthyLife Sciences product, you may return your bottle within 30 days of delivery for a full refund, less shipping costs.  All bottles purchased must be returned.  Refunds will not be given on reorders of the same product.  If multiple bottles are purchased, only unopened bottles will be refunded.  Each customer allowed only one refund."

... which on the face of it, eliminates the risk from your purchase. IF they honor their guarantee and don't make you jump through hoops to receive a refund. That said, I'd love to hear from you. Have you used Healthé Trim? Did you request a refund? Were you refunded promptly and cheerfully? Let us know...

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